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e.g. ENSDARG00000093395 or slc2a11b or ENSG00000135862 or LAMC1 or sa457
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TENC1 (2 of 2)
- Ensembl ID:
- ENSDARG00000068397
- Description:
- tensin like C1 domain containing phosphatase (tensin 2) [Source:HGNC Symbol;Acc:19737]
- Human Orthologue:
- TENC1
- Human Description:
- tensin like C1 domain containing phosphatase (tensin 2) [Source:HGNC Symbol;Acc:19737]
- Mouse Orthologue:
- Tenc1
- Mouse Description:
- tensin like C1 domain-containing phosphatase Gene [Source:MGI Symbol;Acc:MGI:2387586]
Alleles
There are 4 alleles of this gene:
| Allele name | Consequence | Status | Availability Estimate |
|---|---|---|---|
| sa20760 | Essential Splice Site | Available for shipment | Available now |
| sa30625 | Nonsense | Mutation detected in F1 DNA | During 2018 |
| sa2310 | Nonsense | F2 line generated | During 2018 |
| sa38565 | Nonsense | Mutation detected in F1 DNA | During 2018 |
Mutation Details
- Allele Name:
- sa20760
- Current Status:
-
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
- Order Allele From ZIRC
- Mutation:
- G > A
- Consequence:
- Essential Splice Site
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000098906 | Essential Splice Site | 75 | 1333 | 2 | 21 |
- Genomic Location (Zv9):
- Chromosome 6 (position 38968162)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 6 39039762 GRCz11 6 39037298 - KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- None
- Flanking Sequence:
- TTATAAATCTGTCAGAGAAACGTCATGACATCTGCAGGCTAAACCCAAAG[G/A]TATCTTCCTAATTTTAGATGTGCATAAAACCTCTTTTAAATGTCTCTATA
- Associated Phenotype:
- Not determined
Mutation Details
- Allele Name:
- sa30625
- Current Status:
-
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
- We currently estimate that this allele will be available during 2018.
- Mutation:
- A > T
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000098906 | Nonsense | 91 | 1333 | 3 | 21 |
- Genomic Location (Zv9):
- Chromosome 6 (position 38968012)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 6 39039612 GRCz11 6 39037148 - KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- None
- Flanking Sequence:
- CTCAGGTTGAGGAGTTTGGGTGGCCTGATTTGCATGCCCCGCCCCTCGAT[A/T]AAATATGTGCCGTATGCAAGACTATGGAGAACTGGCTTAACTCTGACCCC
- Associated Phenotype:
- Not determined
Mutation Details
- Allele Name:
- sa2310
- Current Status:
-
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
- We currently estimate that this allele will be available during 2018.
- Mutation:
- C > T
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000098906 | Nonsense | 623 | 1333 | 12 | 21 |
- Genomic Location (Zv9):
- Chromosome 6 (position 38957401)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 6 39029001 GRCz11 6 39026537 - KASP Assay ID:
- 554-3083.1 (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- ACAGCACAACATCACCAACTTCATGCTCTTGTCGGGATTGTTTACGATTA[C/T]GAGAGGATGTTGCCCTCCATTCTTTACGAGGAAGGGAATTAGAAACCCTT
- Associated Phenotype:
- Not determined
Mutation Details
- Allele Name:
- sa38565
- Current Status:
-
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
- We currently estimate that this allele will be available during 2018.
- Mutation:
- T > A
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000098906 | Nonsense | 955 | 1333 | 14 | 21 |
- Genomic Location (Zv9):
- Chromosome 6 (position 38954791)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 6 39026391 GRCz11 6 39023927 - KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- None
- Flanking Sequence:
- GACCCTGATGGCTTCATCACACCCTCATTTCCTATAGCATCACACGGCTA[T/A]CCTCTTCTGACGGTGCCTCATGTCCCCTACACAGGCTACACTGAGATCAC
- Associated Phenotype:
- Not determined
GWAS
This gene's human homologue has been identified in the following GWAS studies:
- Prostate cancer: Genome-wide association study identifies new prostate cancer susceptibility loci. (View Study)
(GWAS data comes from http://www.genome.gov/gwastudies/.)
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