irgf3

Ensembl ID:
ENSDARG00000062820
ZFIN ID:
ZDB-GENE-051212-6
Human Orthologues:
IRGC, IRGM
Human Descriptions:
immunity-related GTPase family, cinema [Source:HGNC Symbol;Acc:28835]
immunity-related GTPase family, M [Source:HGNC Symbol;Acc:29597]
Mouse Orthologues:
Ifi47, Irgc1
Mouse Descriptions:
immunity-related GTPase family, cinema 1 Gene [Source:MGI Symbol;Acc:MGI:2685948]
interferon gamma inducible protein 47 Gene [Source:MGI Symbol;Acc:MGI:99448]

Alleles

No alleles have been identified for ENSDARG00000062820 yet.

GWAS

This gene's human homologue has been identified in the following GWAS studies:

  • Crohn's disease: Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. (View Study)
  • Crohn's disease: Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (View Study)
  • Crohn's disease: Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. (View Study)
  • Type 2 diabetes: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. (View Study)
  • Ulcerative colitis: Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

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