tlr9

Ensembl ID:

ENSDARG00000044490

ZFIN ID:

ZDB-GENE-040219-10

Description:

toll-like receptor 9 [Source:RefSeq peptide;Acc:NP_001124066]

Human Orthologues:

RP11-330H6.5, TLR9

Human Descriptions:

TLR9 [Source:UniProtKB/TrEMBL;Acc:C3W5P5]

toll-like receptor 9 [Source:HGNC Symbol;Acc:15633]

Mouse Orthologue:

Tlr9

Mouse Description:

toll-like receptor 9 Gene [Source:MGI Symbol;Acc:MGI:1932389]

Alleles

There are 4 alleles of this gene:

Mutation Details

Allele Name:

sa34528

Current Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

We currently estimate that this allele will be available during 2018.

Mutation:

C > A

Consequence:

Nonsense

Genomic Location (Zv9):

Chromosome 8 (position 55865486)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	53902216
GRCz11	8	53731936

KASP Assay ID:

None (used for ordering genotyping assays from LGC Genomics)

KASP Sequence:

None

Flanking Sequence:

GGCCACCAATTCTCACATCTGAGCAAACTATCTTACCTTAATATGGCGTA[C/A]AACCGTATTGACCTGTATTCCGACAAGGCCTTTCAGGAGGTCAGTGGCAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa1171

Current Status:

Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

We currently estimate that this allele will be available during 2018.

Mutation:

G > A

Consequence:

Nonsense

Genomic Location (Zv9):

Chromosome 8 (position 55865749)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	53901953
GRCz11	8	53731673

KASP Assay ID:

554-1081.1 (used for ordering genotyping assays from LGC Genomics)

KASP Sequence:

GAAGTATCTCATTTTCTCTGGGAATCGTTTGGACATATTGTGGGACTCTT[G/A]GCGTAATCAATACATAAACCTCTTTCAGGGACTCACCAACCTTACGCACT

Associated Phenotype:

Normal

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	whole organism ZFA:0001094	quality PATO:0000001	normal PATO:0000461

Mutation Details

Allele Name:

sa10328

Current Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Nonsense

Genomic Location (Zv9):

Chromosome 8 (position 55866019)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	53901683
GRCz11	8	53731403

KASP Assay ID:

None (used for ordering genotyping assays from LGC Genomics)

KASP Sequence:

TTCRTACTTRCCYAATATTAACWTTGAGCTCCRKCTCACAGGACTGGATT[T/G]AAGTCACAACCGACTGGTTGCAATTCCAAAGGTATTCCTTAGTCAGKCAG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa12600

Current Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

G > A

Consequence:

Nonsense

Genomic Location (Zv9):

Chromosome 8 (position 55866959)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	53900743
GRCz11	8	53730463

KASP Assay ID:

None (used for ordering genotyping assays from LGC Genomics)

KASP Sequence:

AAGTCAGTTCTGTCCTGGCCCAGAAAYCCMYGAGTGCAGCCGCTCTTCTG[G/A]AATGACCTGCGCGTCGCTCTCGTTTCTGACAATRTTAGAGCCTACAACAA

Associated Phenotype:

Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

• Bipolar disorder: Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

OMIM

OMIM information for TLR9

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below: