irf1

Ensembl ID:
ENSDARG00000043492
ZFIN ID:
ZDB-GENE-060421-4031
Description:
interferon regulatory factor 1 [Source:RefSeq peptide;Acc:NP_001035442]
Human Orthologues:
IRF1, IRF2
Human Descriptions:
interferon regulatory factor 1 [Source:HGNC Symbol;Acc:6116]
interferon regulatory factor 2 [Source:HGNC Symbol;Acc:6117]
Mouse Orthologues:
Irf1, Irf2
Mouse Descriptions:
interferon regulatory factor 1 Gene [Source:MGI Symbol;Acc:MGI:96590]
interferon regulatory factor 2 Gene [Source:MGI Symbol;Acc:MGI:96591]

Alleles

No alleles have been identified for ENSDARG00000043492 yet.

GWAS

This gene's human homologue has been identified in the following GWAS studies:

  • C-reactive protein: Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. (View Study)
  • Crohn's disease: Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. (View Study)
  • Fibrinogen: Association of novel genetic Loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. (View Study)
  • Fibrinogen: Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study. (View Study)
  • Platelet counts: New gene functions in megakaryopoiesis and platelet formation. (View Study)
  • Ulcerative colitis: Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. (View Study)

(GWAS data comes from http://www.genome.gov/gwastudies/.)

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