Search Zebrafish Mutation Project
e.g. ENSDARG00000093395 or slc2a11b or ENSG00000135862 or LAMC1 or sa457
You can look for mutant lines by browsing a complete list or by searching for a particular gene
mxa
- Ensembl ID:
- ENSDARG00000021688
- ZFIN ID:
- ZDB-GENE-030721-5
- Description:
- Interferon-induced GTP-binding protein MxA [Source:UniProtKB/Swiss-Prot;Acc:Q8JH68]
- Human Orthologues:
- AC019294.4, MX1, MX2
- Human Descriptions:
- myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) [Source:HGNC Symb
- myxovirus (influenza virus) resistance 2 (mouse) [Source:HGNC Symbol;Acc:7533]
- Putative UPF0621 protein C [Source:UniProtKB/Swiss-Prot;Acc:A8MV40]
- Mouse Orthologues:
- Mx1, Mx2
- Mouse Descriptions:
- myxovirus (influenza virus) resistance 1 Gene [Source:MGI Symbol;Acc:MGI:97243]
- myxovirus (influenza virus) resistance 2 Gene [Source:MGI Symbol;Acc:MGI:97244]
Alleles
There is 1 allele of this gene:
| Allele name | Consequence | Status | Availability Estimate |
|---|---|---|---|
| sa38242 | Nonsense | Mutation detected in F1 DNA | During 2018 |
Mutation Details
- Allele Name:
- sa38242
- Current Status:
-
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
- We currently estimate that this allele will be available during 2018.
- Mutation:
- G > T
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000103588 | Nonsense | 119 | 632 | 3 | 12 |
| ENSDART00000122566 | Nonsense | 119 | 645 | 3 | 13 |
- Genomic Location (Zv9):
- Chromosome 1 (position 6490147)
- Other Location(s):
-
Assembly Chromosome Position GRCz10 1 6884942 GRCz11 1 7568375 - KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- None
- Flanking Sequence:
- TTGTTAATATCTTATTTCCTATTGTGTTTGCAGCCCAAGATGAGATGGCT[G/T]GAGCAGGTGTTGGTATCAGTGAAGAACTCATCAGTCTGCAGATCACCTCT
- Associated Phenotype:
- Not determined
GWAS
This gene's human homologue has been identified in the following GWAS studies:
- Melanoma: Genome-wide association study identifies three new melanoma susceptibility loci. (View Study)
(GWAS data comes from http://www.genome.gov/gwastudies/.)
Register
If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:
