zgc:77346

Ensembl ID:
ENSDARG00000009257
ZFIN ID:
ZDB-GENE-040426-2307
Description:
protein zer-1 homolog [Source:RefSeq peptide;Acc:NP_998066]
Human Orthologue:
ZER1
Human Description:
zer-1 homolog (C. elegans) [Source:HGNC Symbol;Acc:30960]
Mouse Orthologue:
Zer1
Mouse Description:
zer-1 homolog (C. elegans) Gene [Source:MGI Symbol;Acc:MGI:2442511]

Alleles

There are 4 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa8461 Essential Splice Site Mutation detected in F1 DNA During 2018
sa37191 Nonsense Mutation detected in F1 DNA During 2018
sa43556 Essential Splice Site Mutation detected in F1 DNA During 2018
sa29482 Essential Splice Site Mutation detected in F1 DNA During 2018

Mutation Details

Allele Name:
sa8461
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2018.
Mutation:
A > T
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085341 Essential Splice Site 56 774 2 14
Genomic Location (Zv9):
Chromosome 21 (position 6260)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 157342
GRCz11 21 103440
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
CGTGCGTGCGAATGCTCTGCTTCAGTGAGTGACTCTCTGCTGTACTGTGC[A/T]GGTATATGGATCTGRTGCACACAGACAGTGAGTTTGAGCCGCAGGACGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37191
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2018.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085341 Nonsense 57 774 2 14
Genomic Location (Zv9):
Chromosome 21 (position 6265)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 157347
GRCz11 21 103445
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GTGCGAATGCTCTGCTTCAGTGAGTGACTCTCTGCTGTACTGTGCAGGTA[T/A]ATGGATCTGGTGCACACAGACAGTGAGTTTGAGCCGCAGGACGGCTTCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa43556
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2018.
Mutation:
T > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085341 Essential Splice Site 461 774 6 14
Genomic Location (Zv9):
Chromosome 21 (position 11553)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 162635
GRCz11 21 108733
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GGTCATACAGGTGGTGCTCAACGGCATGGAGCATTACCAGGAGGTCACGG[T/A]GAGAAAACACACACACACTTAAATACATGCGCACATTTATGTGTTAAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa29482
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2018.
Mutation:
T > C
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000085341 Essential Splice Site 533 774 7 14
Genomic Location (Zv9):
Chromosome 21 (position 11905)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 162987
GRCz11 21 109085
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GGTGGACAACGACCACAAGGAGGCGGTGGGGAAGATGGGCTTCGTCAAGG[T/C]GATGCACACACACACACACACACACACACACACACACACAAACACACACG
Associated Phenotype:
Not determined

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