Global Health - Partnerships

We strive to foster equitable and sustainable partnerships with researchers in the developing world to tackle major global health problems in a collaborative manner

The Sanger Institute seeks to tackle major scientific problems through international partnership and data-sharing. In the case of global health research, this is of particular importance: we share capacity and resources and benefit from expertise that can only be attained living and working in the developing world. While large-scale partnerships in genomic research are now the norm in the developed world, they pose particular challenges in the context of global health because of the great disparities that exist in research capacity and infrastructure. To foster equitable and sustainable research partnerships it is necessary to make a long-term investment in training, research capacity building and in the development of equitable policies for data sharing. These considerations are key in all the partnerships that we engage in.

The Sanger Institute serves as a resource centre for global health research partnerships such as MalariaGEN and the African Partnership for Chronic Diseases Research, and has close and longstanding collaborative partnerships with the Wellcome Trust Major Overseas Programmes in Kenya, Malawi, Thailand and Vietnam. As well as these more formal partnerships, we work closely with numerous groups, institutes and individual researchers across the spectrum of global health at a variety of levels and in many different contexts. A selection of these are listed below.


Feature Partnerships

* African Partnership for Chronic Disease Research
APCDR aims to facilitate collaborative epidemiological and genomic research of non-communicable diseases across Sub-Saharan Africa
*Wellcome Trust Major Overseas Programmes
The Sanger Institute works closely with these programmes to conduct research into diseases that cause significant morbidity and mortality in the developing world
* Malaria Genomic Epidemiology Network
MalariaGEN is a data-sharing community working to develop new tools to control malaria by integrating epidemiology with genome science
* MRC Centre for Genomics and Global Health (CGGH)
The CGGH accelerates the translation of large-scale genomic data into meaningful information and effective tools to combat infectious diseases endemic in the developing world

Example Partnerships

* Coalition Against Typhoid
CaT was recently established to advocate the deployment and the development of vaccines against typhoid and other invasive salmonellosis. The WTSI is a CaT member and contributes to disease epidemiology in endemic areas.
*Instituto de Higiene, Montevideo, Uruguay
A core satellite centre for running biannual Pathogen and Human Genetics related Wellcome Trust Overseas Advanced Courses, acting as a hub for South American scientists.
*International Vaccine Institute
IVI facilitates the delivery and validation of vaccines and associated programmes for the poor. Links between IVI and the WTSI have focused around enteric diseases such as shigellosis and cholera.
*Novartis Vaccines Institute for Global Health
NVGH facilitates the development of vaccines against neglected diseases such as typhoid and shigellosis. WTSI has a joint EU grant and an open agreement with NVGH for scientific exchange of personnel and reagents.
*PATH Malaria Vaccine Initiative
WTSI are producing libraries of recombinant P. falciparum proteins and working with PATH-MVI with the aim of developing novel anti-malarial vaccines.
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