Dr Vijay Baskar

Mahalingam Shanmugiah, Vijay

I work in hematopoiesis and hematopoietic malignancies in human cell lines, patients and mouse models. My area of expertise is analysis of high throughput genomics data and large scale data integration.

Publications

  • SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.

    Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar MS et al.

    Nature communications 2018;9;1;5378

  • Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib.

    Quek L, David MD, Kennedy A, Metzner M, Amatangelo M et al.

    Nature medicine 2018;24;8;1167-1177

  • A PQM-1-Mediated Response Triggers Transcellular Chaperone Signaling and Regulates Organismal Proteostasis.

    O'Brien D, Jones LM, Good S, Miles J, Vijayabaskar MS et al.

    Cell reports 2018;23;13;3905-3919

  • Chromatin Accessibility-Based Characterization of the Gene Regulatory Network Underlying Plasmodium falciparum Blood-Stage Development.

    Toenhake CG, Fraschka SA, Vijayabaskar MS, Westhead DR, van Heeringen SJ and Bártfai R

    Cell host & microbe 2018;23;4;557-569.e9

  • Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.

    Dovey OM, Cooper JL, Mupo A, Grove CS, Lynn C et al.

    Blood 2017;130;17;1911-1922

  • Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.

    Dovey OM, Cooper JL, Mupo A, Grove CS, Lynn C et al.

    Blood 2017;130;17;1911-1922

  • Introduction to Hidden Markov Models and Its Applications in Biology.

    Vijayabaskar MS

    Methods in molecular biology (Clifton, N.J.) 2017;1552;1-12

  • Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data.

    Shar NA, Vijayabaskar MS and Westhead DR

    Molecular cancer 2016;15;1;76

  • Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.

    Goode DK, Obier N, Vijayabaskar MS, Lie-A-Ling M, Lilly AJ et al.

    Developmental cell 2016;36;5;572-87

  • A histidine aspartate ionic lock gates the iron passage in miniferritins from Mycobacterium smegmatis.

    Williams SM, Chandran AV, Vijayabaskar MS, Roy S, Balaram H et al.

    The Journal of biological chemistry 2014;289;16;11042-58

  • RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.

    Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D et al.

    The EMBO journal 2012;31;22;4318-33

  • Insights into the fold organization of TIM barrel from interaction energy based structure networks.

    Vijayabaskar MS and Vishveshwara S

    PLoS computational biology 2012;8;5;e1002505

  • Interaction energy based protein structure networks.

    Vijayabaskar MS and Vishveshwara S

    Biophysical journal 2010;99;11;3704-15

  • Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks.

    Vijayabaskar MS and Vishveshwara S

    BMC bioinformatics 2010;11 Suppl 1;S49

  • SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4.

    Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar MS et al.

    Nature communications 2018;9;1;5378

  • Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib.

    Quek L, David MD, Kennedy A, Metzner M, Amatangelo M et al.

    Nature medicine 2018;24;8;1167-1177

  • A PQM-1-Mediated Response Triggers Transcellular Chaperone Signaling and Regulates Organismal Proteostasis.

    O'Brien D, Jones LM, Good S, Miles J, Vijayabaskar MS et al.

    Cell reports 2018;23;13;3905-3919

  • Chromatin Accessibility-Based Characterization of the Gene Regulatory Network Underlying Plasmodium falciparum Blood-Stage Development.

    Toenhake CG, Fraschka SA, Vijayabaskar MS, Westhead DR, van Heeringen SJ and Bártfai R

    Cell host & microbe 2018;23;4;557-569.e9

  • Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.

    Dovey OM, Cooper JL, Mupo A, Grove CS, Lynn C et al.

    Blood 2017;130;17;1911-1922

  • Introduction to Hidden Markov Models and Its Applications in Biology.

    Vijayabaskar MS

    Methods in molecular biology (Clifton, N.J.) 2017;1552;1-12

  • Cancer somatic mutations cluster in a subset of regulatory sites predicted from the ENCODE data.

    Shar NA, Vijayabaskar MS and Westhead DR

    Molecular cancer 2016;15;1;76

  • Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.

    Goode DK, Obier N, Vijayabaskar MS, Lie-A-Ling M, Lilly AJ et al.

    Developmental cell 2016;36;5;572-87

  • A histidine aspartate ionic lock gates the iron passage in miniferritins from Mycobacterium smegmatis.

    Williams SM, Chandran AV, Vijayabaskar MS, Roy S, Balaram H et al.

    The Journal of biological chemistry 2014;289;16;11042-58

  • RUNX1 reshapes the epigenetic landscape at the onset of haematopoiesis.

    Lichtinger M, Ingram R, Hannah R, Müller D, Clarke D et al.

    The EMBO journal 2012;31;22;4318-33

  • Insights into the fold organization of TIM barrel from interaction energy based structure networks.

    Vijayabaskar MS and Vishveshwara S

    PLoS computational biology 2012;8;5;e1002505

  • Interaction energy based protein structure networks.

    Vijayabaskar MS and Vishveshwara S

    Biophysical journal 2010;99;11;3704-15

  • Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks.

    Vijayabaskar MS and Vishveshwara S

    BMC bioinformatics 2010;11 Suppl 1;S49

Mahalingam Shanmugiah, Vijay
Vijay's Timeline
2017

Senior Bioinformatician

2011

Post-doctoral Research Fellow, University of Leeds (BBSRC)

2006

Research Fellow, Indian Institute of Science

Junior Research Fellow, Indian Institute of Science

2004

BEngg. PSG Tech