Dr Thomas Keane | Former Senior Scientific Manager

This person is a member of Sanger Institute Alumni.

Keane, Thomas

In November 2016 Dr Thomas Keane moved from the Sanger Institute to EMBL-EBI to run the European Genome-phenome Archive (EGA) and the European Nucleotide Archive (ENA). Find out more here

Thomas led the Sequence Variation Infrastructure group in the Computational Genomics programme. His interests were in using genomic technologies to learn about biological processes with a particular focus on mouse and human disease.


  • Mouse genomic variation and its effect on phenotypes and gene regulation.

    Keane TM, Goodstadt L, Danecek P, White MA, Wong K et al.

    Nature 2011;477;7364;289-94

  • Sequence-based characterization of structural variation in the mouse genome.

    Yalcin B, Wong K, Agam A, Goodson M, Keane TM et al.

    Nature 2011;477;7364;326-9

  • The genomic landscape shaped by selection on transposable elements across 18 mouse strains.

    Nellåker C, Keane TM, Yalcin B, Wong K, Agam A et al.

    Genome biology 2012;13;6;R45

  • Sequencing and characterization of the FVB/NJ mouse genome.

    Wong K, Bumpstead S, Van Der Weyden L, Reinholdt LG, Wilming LG et al.

    Genome biology 2012;13;8;R72

  • The Mouse Genomes Project: a repository of inbred laboratory mouse strain genomes.

    Adams DJ, Doran AG, Lilue J and Keane TM

    Mammalian genome : official journal of the International Mammalian Genome Society 2015;26;9-10;403-12

Keane, Thomas
Thomas's Timeline

Moved to EMBL-EBI to head up the EGA and ENA


Established the Sequence Variation Infrastructure Group, Wellcome Trust Sanger Institute


Senior Scientific Manager, Vertebrate Resequencing Informatics Group, Wellcome Trust Sanger Institute


Senior Bioinformatician, Pathogen Genomics, Wellcome Trust Sanger Institute

PhD Biology, National University of Ireland, Maynooth


M.Sc. Computer Science, National University of Ireland, Maynooth


B.Sc. Computer Science and Software Engineering, National University of Ireland, Maynooth