An interest in the evolutionary drivers of divergence and experiencing the power of bioinformatics to test hypotheses during his undergraduate degree, led Chris to a PhD investigating speciation and the evolution of insecticide resistance in malaria vectors using whole genome sequencing. He continues this research on a pan-African scale at the Wellcome Trust Sanger Institute, working on the Anopheles gambiae 1000 Genomes Project (Ag1000g).
Adaptive introgression between Anopheles sibling species eliminates a major genomic island but not reproductive isolation.
Nature communications 2014;5;4248
Genomics and the origin of species.
Nature reviews. Genetics 2014;15;3;176-92
Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae.
Molecular ecology 2015;24;11;2656-72
Evolving the world's most dangerous animal.
Trends in parasitology 2015;31;2;39-40