News Archive

News Archive

Cattle Parasite Code Cracked

Cattle Parasite Code Cracked

Theileria genome is another step towards reducing disease burden in Africa

On, Friday 1 July 2005, in Science, two teams publish the genomes of parasites that threaten more than 250 million cattle, leading to major economic burdens in Africa, across the Mediterranean region, through the Middle East into India and China. Theileria annulata , which causes tropical theileriosis, is described by a team of scientists, led by researchers at the Wellcome Trust Sanger Institute.

The Constitution of a New Model Army

The Constitution of a New Model Army

Genome basis of working together for a common good

Today, Thursday 5 May 2005, the biological constitution of a remarkable organism that votes with its feet is published in Nature by a team of scientists from the UK, USA, Germany, Japan and France.

The cryptic past of Madagascar

The cryptic past of Madagascar

Human inhabitants of Madagascar are genetically unique

Half of the genetic lineages of human inhabitants of Madagascar come from 4500 miles away in Borneo, while the other half derive from East Africa, according to a study published in May by a UK team

New insights into Chlamydial Infection

New insights into Chlamydial Infection

Genome decoded of sheep pathogen

Today, the hiding places for that killer - a bacterium called Chlamydophila abortus - are fewer because of the genome sequence produced in a collaboration between the Wellcome Trust Sanger Institute, the Moredun Research Institute and the Scottish Crop Research Institute.

Deletion, Duplication and Detail

Deletion, Duplication and Detail

Uncovering Variation in the Human Genomes

In a major new development, published in the American Journal of Human Genetics on Monday April 4, 2005, researchers from the Wellcome Trust Sanger Institute and colleagues describe a new method called 'Exon Array CGH' (comparative genome hybridization) to detect loss or gain of DNA regions across the genome using a DNA 'chip' or array method.

What Sex did to the X - and Why

What Sex did to the X - and Why

A chromosome account of evolution and revolution

On Thursday 17 March 2005, an international team led by the Wellcome Trust Sanger Institute, Cambridge, UK publishes in Nature the most complete analysis of this remarkable chromosome. The landmark study shows how we got an X chromosome and how it has been preserved (while the Y chromosome has degenerated). It also identifies new genes involved in disease and provides a gold-standard platform for studies to understand, to diagnose and, it is hoped, to treat a huge range of human disease.

Genome centres combine forces to validate a gene set for biomedical research

Genome centres combine forces to validate a gene set for biomedical research

Consensus CoDing Sequence - CCDS

Online databases to access the human genome have been a boon to biomedical research, and the usefulness of this information has just moved to a new level. Today researchers at the Wellcome Trust Sanger Institute and the European Bioinformatics Institute (EBI), both at Hinxton Cambridge, together with colleagues at the University of California, Santa Cruz and the National Center for Biotechnology Information (NCBI) in the US have released the results of a project to identify a core set of genes that can be located on the genome and validated as coding for proteins.

DNA of the tissue destroyer

DNA of the tissue destroyer

Genome clues to amoebic dysentery

Each year, there are an estimated 50 million cases of amoebic dysentery, causing up to 100,000 deaths, mostly in developing countries. On Thursday 24 February 2005, researchers at the Wellcome Trust Sanger Institute and their colleagues reported in Nature magazine the genome sequence of the parasite that causes the disease, Entamoeba histolytica.

COSMIC First Anniversary

COSMIC First Anniversary

Milestone for Cancer Mutation Catalogue

The COSMIC (Catalogue of Somatic Mutations in Cancer) database is one year old on Friday 4 February 2005. COSMIC aims to be a definitive source of information about somatic mutations in cancer.

International HapMap Consortium Releases All Data to the Public

International HapMap Consortium Releases All Data to the Public

HapMap Will Help Identify Genetic Contributions to Disease

The International HapMap Consortium announced today (10th December 2004) at a meeting in Tokyo that all its data will be available without any restrictions, following its success in production of raw data for the Project. The Consortium has removed a defensive mechanism known as a 'click-wrap' license designed to prevent others restricting access to this valuable information.

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