News Archive - 2011

News Archive - 2011

Cholera pandemic's source discovered

Cholera pandemic's source discovered

Researchers have tracked the spread of antibiotic-resistant strains back to the Bay of Bengal

Researchers have used next-generation sequencing to trace the source and explain the spread of the latest (seventh) cholera pandemic. They have also highlighted the impact of the acquisition of resistance to antibiotics on shaping outbreaks and show resistance was first acquired around 1982.

Real-time genomics applied to fatal outbreak

Real-time genomics applied to fatal outbreak

Sanger Institute scientists identify the distinguishing features of Klebsiella strain in Dutch hospital outbreak

Two scientists from the Wellcome Trust Sanger Institute have been helping to identify the strain of a highly antibiotic-resistant bacterium at a Dutch hospital which infected more than 80 patients, of which 27 have died. It is the first time that real-time genomics has been applied for diagnostics during an outbreak.

Molecular relay race drives cell cycle

Molecular relay race drives cell cycle

Researchers have probed deep inside the cell's control mechanism using a novel approach to understand temporal aspects of the full cell cycle

Scientists at the Wellcome Trust Sanger Institute and the Wellcome Trust Gurdon Institute discovered that the cycle of cell division is controlled by a molecular handover of substrates of cyclin-dependent kinases by a family of cyclin molecules.

Unique immune system in Atlantic cod

Unique immune system in Atlantic cod

Researchers find that an important component of the immune system is missing in Atlantic cod

An international team of researchers has used high-throughput sequencing technology to make a striking discovery that changes fundamental ideas about the evolution of the immune system in vertebrates. These results are published in Nature.

New resource to unlock the role of microRNAs

New resource to unlock the role of microRNAs

Comprehensive set of mutated mouse microRNAs will drive research

A new resource to define the roles of microRNAs is announced today in Nature Biotechnology. The resource, called mirKO, gives researchers access to tools to investigate the biological role and significance for human health of these enigmatic genes.

Elusive gene discovered that makes platelets grey

Elusive gene discovered that makes platelets grey

Researchers have identified an elusive gene responsible for Grey Platelet Syndrome, an extremely rare blood disorder, which is hoped will make it easier to diagnose

Researchers have identified an elusive gene responsible for Grey Platelet Syndrome, an extremely rare blood disorder in which only about 50 known cases have been reported. As a result, it is hoped that future cases will be easier to diagnose with a DNA test.

Dr Richard Durbin awarded Fellowship by the International Society for Computational Biology

Dr Richard Durbin awarded Fellowship by the International Society for Computational Biology

Sanger Institute researcher is honoured for his work in computational biology and bioinformatics

Richard was nominated for the award by members of the ISCB for his excellence in research and service to the ISCB community. His work has developed cutting-edge computational techniques and approaches to biological investigation for more than 25 years.

Institute researcher awarded Cancer Research UK Fellowship

Institute researcher awarded Cancer Research UK Fellowship

David Adams' research into colorectal cancer wins award

Cancer Research UK has awarded one of its Senior Cancer Research Fellowships for 2011 to Dr David Adams, a cancer researcher at the Wellcome Trust Sanger Institute. The £1.7 million award will support Dr Adams' research into colorectal (bowel) cancer for six years.

New elegant technique used for genomic archaeology

New elegant technique used for genomic archaeology

Algorithm provides new insights into evolutionary exodus out of Africa

One key finding from the Wellcome Trust Sanger Institute's study is that African and non-African populations continued to exchange genetic material well after migration out of Africa 60,000 years ago. This shows that interbreeding between these groups continued long after the original exodus.

ICGC releases new genomic data on cancer ahead of schedule

ICGC releases new genomic data on cancer ahead of schedule

ICGC genomic data release exceeds expected levels in its decade-long programme to generate high-quality sequence for 25,000 tumours

The International Cancer Genome Consortium (ICGC) today announced its sixth major data release at a meeting in Kyoto, Japan. The ICGC also announced that it is ahead of schedule in its decade-long programme to generate high-quality genomic data on more than 25,000 tumours for up to 50 types of cancer that are of clinical and societal importance across the globe.

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