ESGI High throughput sequencing analysis tools
This web page contains information about bioinformatics and computational tools available for the analysis of high-throughput genomic data.
We have identified analysis tools in use at the centres involved in the ESGI network, and have classified them into categories below. In each case there is a brief description, together with links to the home pages for the relevant software package which support download and provide documentation and references.
The use of these tools can be automated with pipeline management software, which let you define a certain workflow and then push data through that pipeline. A pipeline manager ensures that all the tools in the pipeline get run successfully, spreading the work load over a compute cluster. VRPipe was used at the Sanger Institute to do the bulk of the data processing for the 1000 Genomes Project, and can be used to run any of the software packages listed below. A detailed guide for using VRPipe in Amazon's cloud is available, enabling those centres with limited local computing infrastructure to carry out large-scale analyses.
This web page is maintained by Yasin Memari on behalf of ESGI WP4.