ARNIE - AVEXIS Receptor Network with Integrated Expression

ARNIE - AVEXIS Receptor Network with Integrated Expression

ARNIE - AVEXIS Receptor Network with Integrated Expression

Overview

ARNIE is an online database that integrates the extracellular protein interaction network generated in our lab using AVEXIS technology with spatiotemporal expression patterns for all genes in the network. This online tool allows users to browse the network by clicking on individual proteins, or by specifying the spatiotemporal parameters using the drop-down menus. Clicking on connector lines will allow users to compare stage-matched expression patterns for genes encoding interacting proteins. Additionally, users can rapidly search for their genes in the network using the BLAST server provided.

Download and Installation

ARNIE data is accessible here

Learn and Support

An online tutorial video for the AVidity-based EXtracellular Interaction Screen (AVEXIS) technique:

www.jove.com/video/3881/avidity-based-extracellular-interaction-screening-avexis-for-scalable

Publications

  • Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling.

    Martin S, Söllner C, Charoensawan V, Adryan B, Thisse B et al.

    Molecular & cellular proteomics : MCP 2010;9;12;2654-65

Tool Type