GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study for primary open angle glaucoma and macular degeneration reveals novel Loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
aspm ASPM ENSDARG00000071442 15 Not determined 1
cfh CFH ENSDARG00000075761 1 Not determined 12
cfh CFHR3 ENSDARG00000075761 1 Not determined 4
cfh CFHR4 ENSDARG00000075761 1 Not determined 3
cfh CFHR2 ENSDARG00000075761 1 Not determined 1
cfh CFHR5 ENSDARG00000075761 1 Not determined 2
cfhl1 CFH ENSDARG00000056771 None Not determined 12
cfhl1 CFHR3 ENSDARG00000056771 None Not determined 4
cfhl1 CFHR4 ENSDARG00000056771 None Not determined 3
cfhl1 CFHR2 ENSDARG00000056771 None Not determined 1
cfhl1 CFHR5 ENSDARG00000056771 None Not determined 2
cfhl2 CFH ENSDARG00000056778 3 Not determined 12
cfhl2 CFHR3 ENSDARG00000056778 3 Not determined 4
cfhl2 CFHR4 ENSDARG00000056778 3 Not determined 3
cfhl2 CFHR2 ENSDARG00000056778 3 Not determined 1
cfhl2 CFHR5 ENSDARG00000056778 3 Not determined 2
cfhl3 CFH ENSDARG00000094661 None Not determined 12
cfhl3 CFHR3 ENSDARG00000094661 None Not determined 4
cfhl3 CFHR4 ENSDARG00000094661 None Not determined 3
cfhl3 CFHR2 ENSDARG00000094661 None Not determined 1
cfhl3 CFHR5 ENSDARG00000094661 None Not determined 2
cfhl4 CFH ENSDARG00000094496 None Not determined 12
cfhl4 CFHR3 ENSDARG00000094496 None Not determined 4
cfhl4 CFHR4 ENSDARG00000094496 None Not determined 3
cfhl4 CFHR2 ENSDARG00000094496 None Not determined 1
cfhl4 CFHR5 ENSDARG00000094496 None Not determined 2
F13B F13B ENSDARG00000086724 None Not determined 2
htra1a HTRA1 ENSDARG00000032831 5 Normal 9
htra1b HTRA1 ENSDARG00000014907 3 Not determined 9
KCNT2 (2 of 2) KCNT2 ENSDARG00000091352 None Not determined 2
LOC565691 KCNT2 ENSDARG00000074551 2 Not determined 2
LOC568327 KCNT2 ENSDARG00000075812 2 Not determined 2
plekha1 PLEKHA1 ENSDARG00000030064 1 Not determined 2
PLEKHA1 (2 of 2) PLEKHA1 ENSDARG00000094504 None Not determined 2
Q1RLV8_DANRE ZBTB41 ENSDARG00000054984 4 Not determined 1
Q5RI69_DANRE CFH ENSDARG00000094134 None Not determined 12
Q5RI69_DANRE CFHR3 ENSDARG00000094134 None Not determined 4
Q5RI69_DANRE CFHR4 ENSDARG00000094134 None Not determined 3
Q5RI69_DANRE CFHR2 ENSDARG00000094134 None Not determined 1
Q5RI69_DANRE CFHR5 ENSDARG00000094134 None Not determined 2
si:dkey-114d20.1 CFH ENSDARG00000092786 None Not determined 12
si:dkey-114d20.1 CFHR3 ENSDARG00000092786 None Not determined 4
si:dkey-114d20.1 CFHR4 ENSDARG00000092786 None Not determined 3
si:dkey-114d20.1 CFHR2 ENSDARG00000092786 None Not determined 1
si:dkey-114d20.1 CFHR5 ENSDARG00000092786 None Not determined 2
si:dkey-114d20.3 CFH ENSDARG00000091868 None Not determined 12
si:dkey-114d20.3 CFHR3 ENSDARG00000091868 None Not determined 4
si:dkey-114d20.3 CFHR4 ENSDARG00000091868 None Not determined 3
si:dkey-114d20.3 CFHR2 ENSDARG00000091868 None Not determined 1
si:dkey-114d20.3 CFHR5 ENSDARG00000091868 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • ARMS2
  • CFHR1P
* quick link - http://q.sanger.ac.uk/fp3mjfyo