GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A9JR91_DANRE TGM6 ENSDARG00000074155 None Not determined 1
AFF1 AFF1 ENSDARG00000086044 1 Not determined 4
ankrd55 ANKRD55 ENSDARG00000053869 4 Not determined 6
arhgap20 ARHGAP20 ENSDARG00000089326 1 Not determined 3
arhgap20b ARHGAP20 ENSDARG00000093708 None Not determined 3
bcas3 BCAS3 ENSDARG00000054893 2 Normal 8
bcas3 BCAS3 ENSDARG00000090764 None Not determined 8
bzw2 BZW2 ENSDARG00000035918 1 Not determined 1
CACNA1G CACNA1G ENSDARG00000089913 1 Not determined 1
camk4 CAMK4 ENSDARG00000005372 None Not determined 2
cradd CRADD ENSDARG00000028192 None Not determined 2
CSMD1 CSMD1 ENSDARG00000058353 1 Not determined 12
ctnna2 CTNNA2 ENSDARG00000024785 4 Not determined 3
cycs CYCS ENSDARG00000095636 None Not determined 1
DMXL1 (2 of 2) DMXL1 ENSDARG00000063415 None Not determined 1
DMXL1 (1 of 2) DMXL1 ENSDARG00000088990 None Not determined 1
exoc4 EXOC4 ENSDARG00000004336 2 Not determined 2
FMN2 (2 of 2) FMN2 ENSDARG00000023318 1 Not determined 2
fmn2b FMN2 ENSDARG00000061778 1 Not determined 2
GPC6 (4 of 4) GPC6 ENSDARG00000090456 None Not determined 9
GPC6 (3 of 4) GPC6 ENSDARG00000036468 2 Not determined 9
GPC6 (2 of 4) GPC6 ENSDARG00000086960 None Not determined 9
HECW1 (2 of 2) HECW1 ENSDARG00000090795 1 Not determined 2
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
LOC100005846 ELMO1 ENSDARG00000055400 None Not determined 8
LOC100332381 CAMK4 ENSDARG00000078504 1 Not determined 2
LOC557494 SLC4A8 ENSDARG00000015531 None Not determined 1
LOC567057 GABRG3 ENSDARG00000017545 3 Not determined 2
man2a1 MAN2A1 ENSDARG00000059669 5 Not determined 1
megf10 MEGF10 ENSDARG00000017229 5 1 phenotype 1
mrpl10 MRPL10 ENSDARG00000045091 1 Not determined 1
myo16 MYO16 ENSDARG00000078582 1 Not determined 5
ncs1a NCS1 ENSDARG00000055229 None Not determined 1
ncs1b NCS1 ENSDARG00000054186 2 Not determined 1
NP_998256.1 ELMO1 ENSDARG00000019258 3 Not determined 8
osbpl7 OSBPL7 ENSDARG00000012981 3 Not determined 2
parvb PARVB ENSDARG00000019117 None Not determined 3
PLEKHG1 PLEKHG1 ENSDARG00000063484 None Not determined 4
ppapdc1a PPAPDC1A ENSDARG00000067798 None Not determined 1
psma1 PSMA1 ENSDARG00000074076 None Not determined 1
rras2 RRAS2 ENSDARG00000036252 None Not determined 1
sap30l SAP30L ENSDARG00000030213 None Not determined 2
si:ch211-106n13.1 HECW1 ENSDARG00000004291 5 Not determined 2
si:ch211-137a8.2 CLMN ENSDARG00000068926 3 Normal 4
si:dkey-72g4.1 NKAIN2 ENSDARG00000069427 None Not determined 3
spon1a SPON1 ENSDARG00000010029 1 Normal 3
spon1b SPON1 ENSDARG00000023694 1 Not determined 3
ST18 ST18 ENSDARG00000091410 1 Not determined 1
tspan13a TSPAN13 ENSDARG00000068883 1 Not determined 1
tspan13b TSPAN13 ENSDARG00000070479 1 Not determined 1
zgc:100920 NKAIN2 ENSDARG00000042961 1 Not determined 3
zgc:100997 CLMN ENSDARG00000043667 1 Not determined 4
zgc:171629 GPC6 ENSDARG00000091739 None Not determined 9
zgc:171879 VAT1L ENSDARG00000002502 None Not determined 1
zgc:77358 SP6 ENSDARG00000090586 None Not determined 1
zgc:86706 CYCS ENSDARG00000044562 1 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • ANO4
  • FLJ33630
  • FLJ45256
  • LIMS2
  • LOC390956
  • MOBP
  • PDE7B
  • PGAM5P1
  • PRRC2C
  • STK32B
* quick link - http://q.sanger.ac.uk/gq5plsxz