GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcb3l1 TAP2 ENSDARG00000036787 2 Normal 3
adcy3 ADCY3 ENSDARG00000017437 2 Not determined 6
ADCY3 (1 of 2) ADCY3 ENSDARG00000077145 None Not determined 6
bmp3 BMP3 ENSDARG00000060526 None Not determined 3
dab1a DAB1 ENSDARG00000059939 2 Not determined 3
dab1b DAB1 ENSDARG00000003290 2 Not determined 3
ddx55 DDX55 ENSDARG00000009864 1 Not determined 1
dnajc27 DNAJC27 ENSDARG00000070916 1 Not determined 4
grma GRM6 ENSDARG00000025671 2 Not determined 1
LIN28B LIN28B ENSDARG00000052511 None Not determined 11
LOC556339 PRKG2 ENSDARG00000062839 2 Not determined 4
LOC556826 TAP2 ENSDARG00000033446 3 Not determined 3
mapk3 MAPK3 ENSDARG00000070573 2 Not determined 1
nucks1b NUCKS1 ENSDARG00000012777 None Not determined 4
pomca POMC ENSDARG00000043135 None Not determined 4
pomcb POMC ENSDARG00000069307 1 Not determined 4
prkg2 PRKG2 ENSDARG00000054741 1 Not determined 4
si:busm1-160c18.1 HLA-DRA ENSDARG00000053739 None Not determined 21
si:busm1-194e12.11 HLA-DRA ENSDARG00000055441 None Not determined 21
si:busm1-228j01.3 HLA-DRA ENSDARG00000086294 3 Not determined 21
si:busm1-228j01.5 HLA-DRA ENSDARG00000079593 1 Not determined 21
si:ch1073-403i13.1 HLA-DRA ENSDARG00000001832 None Not determined 21
si:ch73-160h15.3 DLEU7 ENSDARG00000094160 None Not determined 6
si:ch73-211l2.3 HLA-DRA ENSDARG00000075932 1 Not determined 21
si:dkey-121j17.5 PRKG2 ENSDARG00000014232 5 Not determined 4
si:dkey-201c13.4 TRPM3 ENSDARG00000039181 5 Not determined 2
si:dkey-267j14.4 TNNI3K ENSDARG00000086933 None Not determined 2
si:dkey-52h10.3 GRM6 ENSDARG00000017742 2 Not determined 1
si:dkeyp-2h4.2 HLA-DRA ENSDARG00000031745 None Not determined 21
si:zfos-2070c2.1 HLA-DRA ENSDARG00000070206 None Not determined 21
si:zfos-367g9.1 HLA-DRA ENSDARG00000074816 1 Not determined 21
socs2 SOCS2 ENSDARG00000045557 1 Not determined 4
TMEM38B TMEM38B ENSDARG00000041562 None Not determined 5
vars2 VARS2 ENSDARG00000056717 2 Not determined 2
VGLL3 VGLL3 ENSDARG00000038305 1 Not determined 4
wu:fc07e02 NUCKS1 ENSDARG00000078473 None Not determined 4
wu:fe37d09 HIST4H4 ENSDARG00000086555 None Not determined 1
wu:fe37d09 HIST4H4 ENSDARG00000091313 None Not determined 1
wu:fe38f03 HIST4H4 ENSDARG00000074631 None Not determined 1
wu:fe38f03 HIST4H4 ENSDARG00000075366 None Not determined 1
wu:fe38f03 HIST4H4 ENSDARG00000087543 None Not determined 1
wu:fe38f03 HIST4H4 ENSDARG00000089684 None Not determined 1
wu:fe38f03 HIST4H4 ENSDARG00000090591 None Not determined 1
zgc:101577 C6orf106 ENSDARG00000078075 None Not determined 4
zgc:123107 HLA-DRA ENSDARG00000020286 None Not determined 21
zgc:165555 HIST4H4 ENSDARG00000086076 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000087472 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000087670 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000089437 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000089737 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000090521 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000090941 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000091011 None Not determined 1
zgc:165555 HIST4H4 ENSDARG00000091446 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • C12orf60
  • MAMSTR
  • MICA
  • RAB7L1
  • ST6
  • YAP1
  • ZNF
  • ZNF483
  • ZNF483
* quick link - http://q.sanger.ac.uk/7iml02t3