GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
adam19b ADAM19 ENSDARG00000067545 None Not determined 2
adamtsl7 THSD4 ENSDARG00000055439 None Not determined 3
armc2 ARMC2 ENSDARG00000022660 4 Not determined 2
ASTN2 (3 of 3) ASTN2 ENSDARG00000090831 None Not determined 9
ASTN2 (2 of 3) ASTN2 ENSDARG00000086640 None Not determined 9
ASTN2 (1 of 3) ASTN2 ENSDARG00000089410 1 Not determined 9
BTNL9 MOG ENSDARG00000067794 None Not determined 2
c10orf11 C10orf11 ENSDARG00000057166 1 Not determined 3
cdc123 CDC123 ENSDARG00000075025 1 Not determined 5
DNER DNER ENSDARG00000061031 3 Not determined 1
fance FANCE ENSDARG00000068870 1 Not determined 1
gpr126 GPR126 ENSDARG00000054137 3 1 phenotype 9
gstcd GSTCD ENSDARG00000036494 2 Not determined 3
hdac4 HDAC4 ENSDARG00000041204 3 Not determined 4
hhip HHIP ENSDARG00000060397 1 Not determined 13
HTR4 HTR4 ENSDARG00000061940 1 Not determined 5
im:7139293 FAM13A ENSDARG00000075564 None Not determined 4
INT12_DANRE INTS12 ENSDARG00000089644 None Not determined 2
ints12 INTS12 ENSDARG00000091678 None Not determined 2
LOC100151437 LUM ENSDARG00000088002 None Not determined 1
LOC100332699 HDAC4 ENSDARG00000089416 1 Not determined 4
LOC564522 KCNJ2 ENSDARG00000019418 None Not determined 9
LOC568467 CHRNA3 ENSDARG00000054497 2 Not determined 15
lum LUM ENSDARG00000045580 None Not determined 1
mecom MECOM ENSDARG00000060808 1 Not determined 7
mfap2 MFAP2 ENSDARG00000059367 None Not determined 3
mhc2dab HLA-DQB1 ENSDARG00000079105 None Not determined 24
MMP15 (2 of 2) MMP15 ENSDARG00000051962 1 Not determined 2
MMP15 (1 of 2) MMP15 ENSDARG00000013072 3 Not determined 2
npnt NPNT ENSDARG00000018721 4 Not determined 2
NP_001091732.1 HLA-DQB1 ENSDARG00000071168 1 Not determined 24
pid1 PID1 ENSDARG00000040315 1 Not determined 2
prl PRL ENSDARG00000037946 1 Not determined 2
prl2 PRL ENSDARG00000018744 None Not determined 2
ptch1 PTCH1 ENSDARG00000016404 6 Normal 3
Q1JPZ9_DANRE MUC21 ENSDARG00000079924 None Not determined 3
si:busm1-104n07.3 HLA-DQB1 ENSDARG00000074510 1 Normal 24
si:busm1-160c18.1 HLA-DQA2 ENSDARG00000053739 None Not determined 17
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000053738 None Not determined 24
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000093706 None Not determined 24
si:busm1-194e12.11 HLA-DQA2 ENSDARG00000055441 None Not determined 17
si:busm1-194e12.12 HLA-DQB1 ENSDARG00000055447 None Not determined 24
si:busm1-228j01.3 HLA-DQA2 ENSDARG00000086294 3 Not determined 17
si:busm1-228j01.4 HLA-DQB1 ENSDARG00000088872 1 Not determined 24
si:busm1-228j01.5 HLA-DQA2 ENSDARG00000079593 1 Not determined 17
si:busm1-228j01.6 HLA-DQB1 ENSDARG00000041705 None Not determined 24
si:ch1073-403i13.1 HLA-DQA2 ENSDARG00000001832 None Not determined 17
si:ch211-148j1.1 TNS1 ENSDARG00000020845 6 Not determined 4
si:ch211-69e5.1 DNER ENSDARG00000079519 2 Not determined 1
si:ch211-8c17.5 KCNJ2 ENSDARG00000038373 1 Not determined 9
si:ch73-211l2.3 HLA-DQA2 ENSDARG00000075932 1 Not determined 17
si:ch73-60e21.3 LRP1 ENSDARG00000029146 9 Not determined 6
si:dkey-247m21.3 HTR4 ENSDARG00000001906 3 Not determined 5
si:dkey-27b3.5 ITGA1 ENSDARG00000074316 2 Not determined 5
si:dkey-6e12.6 CFDP1 ENSDARG00000095086 1 Not determined 2
si:dkeyp-2h4.2 HLA-DQA2 ENSDARG00000031745 None Not determined 17
si:zfos-2070c2.1 HLA-DQA2 ENSDARG00000070206 None Not determined 17
si:zfos-2070c2.3 HLA-DQB1 ENSDARG00000076307 None Not determined 24
si:zfos-367g9.1 HLA-DQA2 ENSDARG00000074816 1 Not determined 17
TNS1 (2 of 2) TNS1 ENSDARG00000078842 1 Not determined 4
wu:fd58b11 HLA-DQB1 ENSDARG00000054921 None Not determined 24
wwox WWOX ENSDARG00000007614 1 Not determined 9
zgc:113307 LUM ENSDARG00000044894 2 Not determined 1
zgc:123107 HLA-DQA2 ENSDARG00000020286 None Not determined 17
zgc:153067 HLA-DQB1 ENSDARG00000056330 1 Not determined 24
zgc:66317 PADI3 ENSDARG00000044167 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • AGER
  • ARHGEF
  • ARHGEF
  • BCL6
  • CCDC38
  • DDX1
  • DPCR1
  • DPCR1
  • FAM168A
  • FAM168A
  • KERA
  • MYCN
  • NCR3
  • PLEKHB
  • PLEKHB
  • PPARD
  • PPP1R1
  • PPP1R1
  • RARB
  • RTP2
  • SOX4
  • SOX4
  • SOX9
  • SOX9
  • TXNDC2
  • TXNDC2
  • VAPA
  • VAPA
* quick link - http://q.sanger.ac.uk/5nxxw3vx