GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
bmp2a BMP2 ENSDARG00000013409 None Not determined 7
bmp2b BMP2 ENSDARG00000041430 1 Not determined 7
ccnd2a CCND2 ENSDARG00000051748 None Not determined 7
ccnd2b CCND2 ENSDARG00000070408 None Not determined 7
dcbld1 DCBLD1 ENSDARG00000015907 3 Not determined 4
gopc GOPC ENSDARG00000023117 None Not determined 1
grem1a GREM1 ENSDARG00000029546 None Not determined 3
lamc1 LAMC1 ENSDARG00000036279 5 1 phenotype 1
LOC100005691 DCBLD1 ENSDARG00000087892 None Not determined 4
LOC100005728 GREM1 ENSDARG00000070612 None Not determined 3
LOC100334188 TBX3 ENSDARG00000061509 None Not determined 8
myca MYC ENSDARG00000045695 None Not determined 7
mycb MYC ENSDARG00000007241 None Not determined 7
mych MYC ENSDARG00000077473 None Not determined 7
NP_998017.1 GREM1 ENSDARG00000090720 None Not determined 3
si:dkey-245l10.1 LAMC1 ENSDARG00000093572 None Not determined 1
smad7 SMAD7 ENSDARG00000016858 None Not determined 7
tbx16 TBX3 ENSDARG00000007329 None Not determined 8
tbx3 TBX3 ENSDARG00000002216 3 Normal 8
tbx6 TBX3 ENSDARG00000006939 None Not determined 8
zgc:103502 CCND2 ENSDARG00000027391 None Not determined 7

The following reported genes could not be linked automatically to a zebrafish gene:

  • C1orf110
  • CRAC1
  • HMPS
  • NABP1
* quick link - http://q.sanger.ac.uk/bu7vfquu