GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Seventy-five genetic loci influencing the human red blood cell.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
actl6b ACTL6B ENSDARG00000034107 None Not determined 1
atp5o ATP5O ENSDARG00000001788 2 Not determined 1
B8JLX5_DANRE CALR ENSDARG00000094825 None Not determined 1
bcl11a BCL11A ENSDARG00000061352 2 Normal 10
cacna1c CACNA1C ENSDARG00000008398 4 1 phenotype 7
CACNA1C CACNA1C ENSDARG00000037904 None Not determined 7
calr CALR ENSDARG00000043276 1 Not determined 1
calrl CALR ENSDARG00000020103 1 Not determined 1
calrl2 CALR ENSDARG00000076290 1 Not determined 1
ccnd2a CCND2 ENSDARG00000051748 None Not determined 7
ccnd2b CCND2 ENSDARG00000070408 None Not determined 7
churc1 FNTB ENSDARG00000010831 1 Not determined 2
cited2 CITED2 ENSDARG00000030905 None Not determined 5
dennd4a DENND4A ENSDARG00000062721 3 Not determined 1
eif5 EIF5 ENSDARG00000003681 None Not determined 1
farsa FARSA ENSDARG00000032750 None Not determined 1
fbxo7 FBXO7 ENSDARG00000059115 1 Not determined 1
hbs1l HBS1L ENSDARG00000036778 1 Not determined 11
heyl HEYL ENSDARG00000055798 None Not determined 1
hk1 HK1 ENSDARG00000039452 1 Not determined 4
ikzf1 IKZF1 ENSDARG00000013539 3 Not determined 10
im:7149048 FAM38A ENSDARG00000076870 6 Not determined 1
kita KIT ENSDARG00000043317 2 1 phenotype 3
kitb KIT ENSDARG00000056133 2 Not determined 3
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
LOC100331813 RASA2 ENSDARG00000078775 1 Not determined 2
LOC568267 KCTD17 ENSDARG00000056050 None Not determined 1
march1 MARCH8 ENSDARG00000037487 1 Not determined 2
max MAX ENSDARG00000024844 None Not determined 3
mhc1uba HFE ENSDARG00000075963 None Not determined 20
mhc1ze HFE ENSDARG00000074765 None Not determined 20
mhc1zel HFE ENSDARG00000092162 1 Not determined 20
ncaph2 NCAPH2 ENSDARG00000033757 None Not determined 1
nkx2.3 NKX2-3 ENSDARG00000039095 1 Not determined 10
nkx2.7 NKX2-3 ENSDARG00000021232 1 1 phenotype 10
NP_001009918.2 TFRC ENSDARG00000012552 None Not determined 3
NP_919406.1 HFE ENSDARG00000086877 2 Not determined 20
odf3b ODF3B ENSDARG00000042391 1 Not determined 3
prkag2 PRKAG2 ENSDARG00000001933 1 Not determined 5
prkcea PRKCE ENSDARG00000003008 None Not determined 3
prkceb PRKCE ENSDARG00000069928 2 Not determined 3
ptplad1 PTPLAD1 ENSDARG00000016038 None Not determined 1
Q8MHB3_DANRE HFE ENSDARG00000076734 None Not determined 20
Q8MHB6_DANRE HFE ENSDARG00000088022 None Not determined 20
rbm38 RBM38 ENSDARG00000058818 1 Not determined 3
rcl1 RCL1 ENSDARG00000038312 None Not determined 4
sco2 SCO2 ENSDARG00000045555 None Not determined 2
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:ch211-127m10.2 BCL11A ENSDARG00000063153 2 Not determined 10
si:ch211-205h19.1 ACOXL ENSDARG00000020149 2 Not determined 6
si:ch211-231a1.5 TMPRSS6 ENSDARG00000094087 None Not determined 14
si:ch211-287j19.6 HFE ENSDARG00000001470 1 Not determined 20
si:ch211-5k11.11 NPRL3 ENSDARG00000010918 2 Not determined 3
si:ch73-213j4.4 HFE ENSDARG00000092731 None Not determined 20
si:dkey-165i4.1 ATXN2 ENSDARG00000052897 4 Normal 10
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
SMOC1 (2 of 2) SMOC1 ENSDARG00000088255 None Not determined 1
SMOC1 (1 of 2) SMOC1 ENSDARG00000089188 None Not determined 1
syce2 SYCE2 ENSDARG00000058375 None Not determined 1
tfr1a TFRC ENSDARG00000058784 1 Not determined 3
tfr1b TFRC ENSDARG00000077372 None Not determined 3
TFR2 (2 of 2) TFR2 ENSDARG00000018406 None Not determined 4
TFR2 (1 of 2) TFR2 ENSDARG00000089980 None Not determined 4
thrb THRB ENSDARG00000021163 1 Not determined 1
ube2l3a UBE2L3 ENSDARG00000019188 None Not determined 8
ube2l3b UBE2L3 ENSDARG00000027141 None Not determined 8
ydjc YDJC ENSDARG00000062655 1 Not determined 4
zgc:103502 CCND3 ENSDARG00000027391 None Not determined 6
zgc:103502 CCND2 ENSDARG00000027391 None Not determined 7
zgc:136614 HFE ENSDARG00000069471 None Not determined 20
zgc:153329 PRKAG2 ENSDARG00000012625 None Not determined 5
zgc:171495 MARCH8 ENSDARG00000062489 None Not determined 2
zgc:171724 KIF22 ENSDARG00000077375 1 Not determined 1
zgc:194225 NUDT19 ENSDARG00000077537 None Not determined 2
zgc:64115 HFE ENSDARG00000036588 2 Not determined 20

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABO
  • CCDC162P
  • KITLG
  • LOC645434
  • MIR181A1
  • NRG4
  • OR10Z1
  • OR6Y1
  • PIEZO1
  • SLC17A3
  • TRIM58
  • TYMP
* quick link - http://q.sanger.ac.uk/9c3zzibw