GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcg2a ABCG2 ENSDARG00000043037 None Not determined 10
abcg2b ABCG2 ENSDARG00000079361 None Not determined 10
abcg2c ABCG2 ENSDARG00000058574 3 Not determined 10
abcg2d ABCG2 ENSDARG00000016818 1 Not determined 10
AP3B2 AP3B2 ENSDARG00000063432 1 Not determined 1
apob APOB ENSDARG00000042780 7 Not determined 17
apobl APOB ENSDARG00000022767 6 Not determined 17
apoeb APOE ENSDARG00000040295 None Not determined 42
cetp CETP ENSDARG00000030872 1 Not determined 27
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100333882 RNF213 ENSDARG00000033824 None Not determined 2
plg LPA ENSDARG00000023111 2 Not determined 10
rnf213 RNF213 ENSDARG00000075710 1 Not determined 2
scarb1 SCARB1 ENSDARG00000042697 None Not determined 5
si:dkey-159a18.1 SORT1 ENSDARG00000056145 1 Not determined 13
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-88f5.1 APOB ENSDARG00000075016 3 Not determined 17
sort1a SORT1 ENSDARG00000029402 None Not determined 13
sort1b SORT1 ENSDARG00000056252 7 Not determined 13
tmem49 TMEM49 ENSDARG00000012450 2 Not determined 1
zgc:110064 APOE ENSDARG00000086370 None Not determined 42
zgc:77563 PLA2G7 ENSDARG00000003584 None Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC1
  • C14orf177
  • EDG7
  • MS4A4E
  • NOX5
* quick link - http://q.sanger.ac.uk/yxkoqopw