GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
adh8a ADH4 ENSDARG00000091211 2 Not determined 2
adh8a ADH1B ENSDARG00000091211 2 Not determined 5
adh8b ADH4 ENSDARG00000024278 1 Not determined 2
adh8b ADH1B ENSDARG00000024278 1 Not determined 5
chek2 CHEK2 ENSDARG00000025820 1 Not determined 4
heatr3 HEATR3 ENSDARG00000036076 2 Normal 1
LOC100334034 HAP1 ENSDARG00000074508 None Not determined 1
ptpn2a PTPN2 ENSDARG00000016481 3 Not determined 13
ptpn2b PTPN2 ENSDARG00000035986 2 Not determined 13
slc10a2 SLC10A2 ENSDARG00000014916 1 Normal 2
smg6 SMG6 ENSDARG00000075957 1 Not determined 5
st6gal1 ST6GAL1 ENSDARG00000044514 1 Not determined 4
xbp1 XBP1 ENSDARG00000035622 None Not determined 1
zgc:63568 ADH4 ENSDARG00000087262 2 Not determined 2
zgc:63568 ADH1B ENSDARG00000087262 2 Not determined 5
zgc:77938 ADH4 ENSDARG00000088366 2 Not determined 2
zgc:77938 ADH1B ENSDARG00000088366 2 Not determined 5

The following reported genes could not be linked automatically to a zebrafish gene:

  • IGFB2
* quick link - http://q.sanger.ac.uk/a6a7v07a