GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A8WFQ6_DANRE SLC25A1 ENSDARG00000076381 None Not determined 2
abca1a ABCA1 ENSDARG00000074635 9 Not determined 13
angptl3 ANGPTL3 ENSDARG00000044365 None Not determined 7
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa4 APOA1 ENSDARG00000040298 1 Not determined 13
apoa4 APOA4 ENSDARG00000040298 1 Not determined 11
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
apob APOB ENSDARG00000042780 7 Not determined 17
apobl APOB ENSDARG00000022767 6 Not determined 17
apoeb APOE ENSDARG00000040295 None Not determined 42
aqp9b AQP9 ENSDARG00000053480 1 Not determined 1
ccnb2 CCNB2 ENSDARG00000036180 None Not determined 1
cetp CETP ENSDARG00000030872 1 Not determined 27
CLTCL1 (2 of 2) CLTCL1 ENSDARG00000088853 None Not determined 1
CLTCL1 (1 of 2) CLTCL1 ENSDARG00000091618 4 Not determined 1
cyp4v2 CYP4V2 ENSDARG00000062132 1 Not determined 1
dhx38 DHX38 ENSDARG00000053946 1 Not determined 2
dock7 DOCK7 ENSDARG00000078675 5 Not determined 5
elovl2 ELOVL2 ENSDARG00000045414 None Not determined 4
fads2 FADS2 ENSDARG00000019532 None Not determined 15
gc GC ENSDARG00000089310 None Not determined 5
gls2 GLS2 ENSDARG00000069095 1 Not determined 3
gltpd2 GLTPD2 ENSDARG00000067889 1 Not determined 1
grk5 GRK6 ENSDARG00000032801 None Not determined 3
GSC2 GSC2 ENSDARG00000076491 1 Not determined 1
ldlr LDLR ENSDARG00000029476 1 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
LOC100002437 GLTPD2 ENSDARG00000054218 1 Not determined 1
LOC100151141 RNF111 ENSDARG00000078802 3 Not determined 2
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC561288 GRK6 ENSDARG00000032157 1 Not determined 3
LOC562087 PPM1K ENSDARG00000076011 4 Normal 3
LOC568788 ADAMTS3 ENSDARG00000060127 1 Not determined 4
LOC797748 GLS2 ENSDARG00000062781 None Not determined 3
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 None Not determined 21
myo1e MYO1E ENSDARG00000036179 4 Not determined 1
NP_001185674.1 TM4SF5 ENSDARG00000090943 None Not determined 1
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
pfn1 PFN3 ENSDARG00000088091 None Not determined 3
pltp PLTP ENSDARG00000035768 1 Not determined 5
ppm1k PPM1K ENSDARG00000010655 None Not determined 3
ppp1r3b PPP1R3B ENSDARG00000044691 None Not determined 9
si:ch211-155m12.3 TNKS ENSDARG00000062897 2 Not determined 1
si:ch211-257m21.2 USP24 ENSDARG00000059925 3 Not determined 1
si:ch211-281g13.4 HERC6 ENSDARG00000075389 None Not determined 1
si:ch211-281g13.5 HERC6 ENSDARG00000074052 1 Not determined 1
si:ch73-190m4.1 HERC6 ENSDARG00000075785 3 Not determined 1
si:ch73-386h18.1 ZFHX3 ENSDARG00000073944 3 Not determined 7
si:dkey-102c8.6 GLS2 ENSDARG00000002917 None Not determined 3
si:dkey-162b3.1 GALNT2 ENSDARG00000003829 4 Not determined 8
si:dkey-178e17.1 SLC25A1 ENSDARG00000080000 None Not determined 2
si:dkey-220o5.1 GRK6 ENSDARG00000078815 2 Not determined 3
si:dkey-242g16.2 PPP1R3B ENSDARG00000069377 None Not determined 9
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-7f3.15 APOA1 ENSDARG00000094929 None Not determined 13
si:dkey-7f3.15 APOA4 ENSDARG00000094929 None Not determined 11
si:dkey-7f3.15 APOA5 ENSDARG00000094929 None Not determined 22
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-88f5.1 APOB ENSDARG00000075016 3 Not determined 17
slc1a4 SLC1A4 ENSDARG00000000551 2 Not determined 2
slc25a1 SLC25A1 ENSDARG00000057110 2 Not determined 2
spryd4 SPRYD4 ENSDARG00000023309 None Not determined 1
tat TAT ENSDARG00000069630 2 Not determined 2
tm4sf5 TM4SF5 ENSDARG00000055185 None Not determined 1
tnks TNKS ENSDARG00000077650 5 Not determined 1
tnks TNKS ENSDARG00000095261 1 Not determined 1
ZFHX3 ZFHX3 ENSDARG00000073681 7 Not determined 7
zgc:110064 APOE ENSDARG00000086370 None Not determined 42
zgc:112263 ELOVL2 ENSDARG00000057365 None Not determined 4
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:153394 ELOVL2 ENSDARG00000068551 1 Not determined 4
zgc:154042 CYP4V2 ENSDARG00000061585 1 Not determined 1
zgc:163136 HERC6 ENSDARG00000074136 2 Not determined 1
zgc:171581 ABCA1 ENSDARG00000079009 5 Not determined 13
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:64042 MYO1E ENSDARG00000009133 5 Not determined 1
zgc:77112 PPP1R3B ENSDARG00000015657 None Not determined 9

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC3
  • APOEC1
  • APOEC2
  • CXCL5
  • EREG
  • F12
  • FADS1
  • FADS3
  • G6PC2
  • HP
  • HPR
  • KLKB1
  • PF4
  • PPBP
  • SERPINA1
  • VM01
* quick link - http://q.sanger.ac.uk/bqdm2oya