GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Meta-analysis identifies multiple loci associated with kidney function-related traits in east Asian populations.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5WWE7_DANRE ALDH2 ENSDARG00000037094 None Not determined 12
abcg2a ABCG2 ENSDARG00000043037 None Not determined 10
abcg2b ABCG2 ENSDARG00000079361 None Not determined 10
abcg2c ABCG2 ENSDARG00000058574 3 Not determined 10
abcg2d ABCG2 ENSDARG00000016818 1 Not determined 10
ALDH2 (3 of 4) ALDH2 ENSDARG00000090766 None Not determined 12
aldh2a ALDH2 ENSDARG00000089924 1 Not determined 12
aldh2b ALDH2 ENSDARG00000028087 None Not determined 12
bcas3 BCAS3 ENSDARG00000054893 2 Normal 8
bcas3 BCAS3 ENSDARG00000090764 None Not determined 8
bcl6a BCL6 ENSDARG00000070864 1 Not determined 1
bcl6ab BCL6 ENSDARG00000069295 1 Not determined 1
C12orf51 (3 of 3) C12orf51 ENSDARG00000090715 None Not determined 9
C12orf51 (1 of 3) C12orf51 ENSDARG00000079151 3 Not determined 9
gnas GNAS ENSDARG00000043094 1 Not determined 3
GRIK2 (2 of 2) GRIK2 ENSDARG00000091173 None Not determined 5
GRIK2 (1 of 2) GRIK2 ENSDARG00000074515 None Not determined 5
kbtbd8 KBTBD8 ENSDARG00000070698 1 Not determined 1
LOC100001249 SLC22A12 ENSDARG00000054690 None Not determined 4
LOC100330423 C12orf51 ENSDARG00000003682 2 Not determined 9
lpp LPP ENSDARG00000023578 1 Not determined 10
lrig1 LRIG1 ENSDARG00000075625 6 Normal 3
maf MAF ENSDARG00000015890 1 Not determined 8
MAF (1 of 2) MAF ENSDARG00000076520 1 Not determined 8
mecom MECOM ENSDARG00000060808 1 Not determined 7
mpped2 MPPED2 ENSDARG00000034443 None Not determined 3
mtx1a MTX1 ENSDARG00000025500 1 Not determined 1
mtx1b MTX1 ENSDARG00000036109 None Not determined 1
NP_001107902.1 SLC2A9 ENSDARG00000063288 3 1 phenotype 14
pax8 PAX8 ENSDARG00000015879 1 Not determined 1
Q6NW67_DANRE UNCX ENSDARG00000029117 None Not determined 1
RGS14 (1 of 2) RGS14 ENSDARG00000060200 None Not determined 5
rgs14a RGS14 ENSDARG00000021521 None Not determined 5
SHROOM3 (2 of 2) SHROOM3 ENSDARG00000078705 1 Not determined 6
SHROOM3 (1 of 2) SHROOM3 ENSDARG00000090422 None Not determined 6
si:dkey-119m7.4 SLC22A12 ENSDARG00000071049 4 Normal 4
si:dkey-19n13.4 GBA ENSDARG00000076058 1 Normal 3
slc14a2 SLC14A2 ENSDARG00000051914 2 Not determined 4
slc2a11b SLC2A9 ENSDARG00000093395 2 1 phenotype 14
slc2a15a SLC2A9 ENSDARG00000029894 None Not determined 14
slc2a15b SLC2A9 ENSDARG00000053269 1 Not determined 14
tfap2b TFAP2B ENSDARG00000012667 1 Not determined 5
tmem174 TMEM174 ENSDARG00000035388 None Not determined 1
uncx UNCX ENSDARG00000020961 1 Not determined 1
uncx4.1 UNCX ENSDARG00000037760 None Not determined 1
wu:fd99c08 RBM16 ENSDARG00000074786 None Not determined 1
zgc:112142 MPPED2 ENSDARG00000006889 None Not determined 3
zgc:154018 CNKSR3 ENSDARG00000068613 1 Not determined 2
zgc:162040 RSPO3 ENSDARG00000070081 1 Not determined 7
zgc:172112 CNKSR3 ENSDARG00000074236 3 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • DCDC5
  • DCDC5
  • DCDC5
  • MHC
  • MHC
  • MPPED2l
  • TMEM171
  • UMOD
  • UMOD
  • WDR72
  • WDR72
  • WDR72
* quick link - http://q.sanger.ac.uk/4cl9itev