GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ADAM23 (1 of 2) ADAM23 ENSDARG00000074197 None Not determined 1
cacna1c CACNA1C ENSDARG00000008398 4 1 phenotype 7
CACNA1C CACNA1C ENSDARG00000037904 None Not determined 7
cmklr1 CMKLR1 ENSDARG00000090890 1 Not determined 3
cnnm2a CNNM2 ENSDARG00000061195 2 Not determined 9
cnnm2b CNNM2 ENSDARG00000078733 2 Not determined 9
CSMD1 CSMD1 ENSDARG00000058353 1 Not determined 12
DLC1 DLC1 ENSDARG00000079317 1 Normal 2
dpyd DPYD ENSDARG00000010267 1 Not determined 3
DPYD (4 of 5) DPYD ENSDARG00000086853 None Not determined 3
DPYD (3 of 5) DPYD ENSDARG00000086464 None Not determined 3
DPYD (2 of 5) DPYD ENSDARG00000089675 1 Not determined 3
E2J8V4_DANRE TCF4 ENSDARG00000087652 None Not determined 9
fez1 FEZ1 ENSDARG00000023174 None Not determined 2
gpr1 GPR1 ENSDARG00000063704 1 Not determined 1
im:7149628 MSRA ENSDARG00000055270 None Not determined 6
irf2bp2a IRF2BP2 ENSDARG00000004702 1 Not determined 3
irf2bp2b IRF2BP2 ENSDARG00000006275 1 Not determined 3
kcnmb2 KCNMB2 ENSDARG00000006568 None Not determined 3
LOC100151487 NLRC5 ENSDARG00000088423 None Not determined 2
LOC100333695 NLRC5 ENSDARG00000090946 None Not determined 2
LOC555586 FTSJ2 ENSDARG00000075368 None Not determined 1
LOC566750 NMUR2 ENSDARG00000022570 2 Not determined 2
LOC796753 KCNMB2 ENSDARG00000001712 1 Not determined 3
mad1l1 MAD1L1 ENSDARG00000033852 3 Not determined 3
MMP16 (3 of 3) MMP16 ENSDARG00000025111 None Not determined 4
mmp16a MMP16 ENSDARG00000088118 None Not determined 4
mmp16b MMP16 ENSDARG00000058876 2 Not determined 4
NLRC5 NLRC5 ENSDARG00000024631 6 Not determined 2
NP_001155915.1 SNX8 ENSDARG00000074842 1 Not determined 1
nt5c2a NT5C2 ENSDARG00000039399 3 Not determined 9
nt5c2b NT5C2 ENSDARG00000058231 2 Not determined 9
nudt1 NUDT1 ENSDARG00000030573 1 Not determined 1
pknox2 PKNOX2 ENSDARG00000055349 3 Normal 7
ror2 ROR2 ENSDARG00000076227 1 Not determined 1
si:ch211-160l17.2 PTBP2 ENSDARG00000015901 None Not determined 3
si:ch211-214b16.4 NLRC5 ENSDARG00000093417 None Not determined 2
si:ch211-236p5.2 NLRC5 ENSDARG00000086256 None Not determined 2
si:ch211-236p5.3 NLRC5 ENSDARG00000086418 1 Not determined 2
si:ch211-240b21.4 CMKLR1 ENSDARG00000093228 None Not determined 3
si:ch211-240b21.5 CMKLR1 ENSDARG00000092087 None Not determined 3
si:ch211-278p9.1 NLRC5 ENSDARG00000087532 1 Not determined 2
si:ch211-278p9.2 NLRC5 ENSDARG00000095274 1 Not determined 2
si:ch211-278p9.3 NLRC5 ENSDARG00000094606 None Not determined 2
si:ch211-278p9.4 NLRC5 ENSDARG00000089839 None Not determined 2
si:ch211-66k16.2 NLRC5 ENSDARG00000095634 None Not determined 2
si:ch73-233m11.2 NLRC5 ENSDARG00000091859 None Not determined 2
si:dkey-196n19.1 NLRC5 ENSDARG00000086615 None Not determined 2
si:dkey-221h15.1 MSRA ENSDARG00000029587 1 Not determined 6
si:dkey-31n13.4 NLRC5 ENSDARG00000074202 None Not determined 2
si:dkey-58j15.9 SNX8 ENSDARG00000078057 None Not determined 1
si:dkey-69c19.1 NLRC5 ENSDARG00000089318 None Not determined 2
si:dkeyp-23e4.3 DLC1 ENSDARG00000074819 1 Not determined 2
si:rp71-5o12.3 NLRC5 ENSDARG00000075763 None Not determined 2
SNX8 (3 of 3) SNX8 ENSDARG00000077708 None Not determined 1
sptlc1 SPTLC1 ENSDARG00000042995 1 Not determined 1
TCF4 (1 of 2) TCF4 ENSDARG00000075546 1 Not determined 9
wu:fj40f01 ADAM23 ENSDARG00000062323 3 Not determined 1
zgc:113074 PTBP2 ENSDARG00000015230 2 Not determined 3
zgc:153505 DPYD ENSDARG00000071482 None Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • CENTG2
  • COMMD10
  • El24
  • has-mir-137
  • MHC
  • MHC
  • MHC
  • MHC
  • other genes
  • other genes
  • other genes
  • other genes
  • ZDBF2
* quick link - http://q.sanger.ac.uk/srd0trz6