GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A1A5U5_DANRE DLL4 ENSDARG00000077129 None Not determined 1
A7YY95_DANRE FANK1 ENSDARG00000039657 1 Not determined 1
ADAM12 ADAM12 ENSDARG00000079068 1 Not determined 3
ADAMTS2 (2 of 2) ADAMTS2 ENSDARG00000091328 None Not determined 3
adamts22 ADAMTS2 ENSDARG00000075930 2 Normal 3
adamts9 ADAMTS9 ENSDARG00000077778 5 Not determined 5
adcy2a ADCY2 ENSDARG00000058392 None Not determined 2
adcy2b ADCY2 ENSDARG00000014588 3 Not determined 2
bach1 BACH1 ENSDARG00000002196 None Not determined 2
bach2 BACH2 ENSDARG00000004074 4 Not determined 14
c1galt1a C1GALT1 ENSDARG00000055585 None Not determined 2
c1galt1b C1GALT1 ENSDARG00000055561 None Not determined 2
cadm2a CADM2 ENSDARG00000009930 2 Not determined 3
cct3 CCT3 ENSDARG00000016173 1 1 phenotype 1
cdc73 CDC73 ENSDARG00000020201 3 Not determined 1
cdh10 CDH9 ENSDARG00000055843 2 Normal 5
cdh6 CDH9 ENSDARG00000014522 2 Not determined 5
chac1 CHAC1 ENSDARG00000070426 None Not determined 1
cp CP ENSDARG00000010312 None Not determined 1
cpo CPO ENSDARG00000077688 2 Normal 1
cry-dash CRY2 ENSDARG00000002396 1 Not determined 3
cry3 CRY2 ENSDARG00000079444 None Not determined 3
cry4 CRY2 ENSDARG00000011890 1 Not determined 3
cry5 CRY2 ENSDARG00000019498 1 Not determined 3
cx28.6 GJB5 ENSDARG00000003925 None Not determined 1
cx30.9 GJB5 ENSDARG00000070362 1 Not determined 1
cx34.4 GJB5 ENSDARG00000075854 None Not determined 1
dclk2 DCLK2 ENSDARG00000034093 2 Not determined 1
dkk3 DKK3 ENSDARG00000070683 2 Not determined 1
dll4 DLL4 ENSDARG00000070425 1 Not determined 1
DNAH5 DNAH5 ENSDARG00000087373 8 Not determined 5
eml2 EML2 ENSDARG00000008808 None Not determined 1
eya4 EYA4 ENSDARG00000012397 1 Not determined 3
FA40A_DANRE FAM40A ENSDARG00000074084 None Not determined 1
fabp11a FABP4 ENSDARG00000090113 None Not determined 2
fabp11b FABP4 ENSDARG00000002311 None Not determined 2
fam40a FAM40A ENSDARG00000075460 None Not determined 1
fam84a FAM84A ENSDARG00000018921 None Not determined 1
fam86a FAM86A ENSDARG00000054950 None Not determined 1
fbxl7 FBXL7 ENSDARG00000077878 2 Not determined 3
foxp1a FOXP1 ENSDARG00000004843 None Not determined 2
foxp1b FOXP1 ENSDARG00000014181 2 Not determined 2
fto FTO ENSDARG00000044216 2 Not determined 32
GIPR GIPR ENSDARG00000025478 2 Not determined 5
gpatch2 GPATCH2 ENSDARG00000031064 None Not determined 2
GPC6 (4 of 4) GPC6 ENSDARG00000090456 None Not determined 9
GPC6 (3 of 4) GPC6 ENSDARG00000036468 2 Not determined 9
GPC6 (2 of 4) GPC6 ENSDARG00000086960 None Not determined 9
hapln1a HAPLN1 ENSDARG00000089769 None Not determined 3
hapln1b HAPLN1 ENSDARG00000068516 3 Not determined 3
hspa12b HSPA12B ENSDARG00000030307 None Not determined 1
htr2a HTR2A ENSDARG00000057029 4 Not determined 2
igfbp5a IGFBP5 ENSDARG00000039264 None Not determined 2
igfbp5b IGFBP5 ENSDARG00000025348 None Not determined 2
im:6903007 MIPEP ENSDARG00000055339 None Not determined 3
irx6a IRX6 ENSDARG00000034420 3 Normal 1
kcnd3 KCND3 ENSDARG00000056101 1 Not determined 3
kcnh5a KCNH5 ENSDARG00000043220 2 Not determined 2
KIAA0146 KIAA0146 ENSDARG00000086681 None Not determined 1
large LARGE ENSDARG00000005126 None Not determined 1
LOC100001249 SLC22A8 ENSDARG00000054690 None Not determined 1
LOC100002527 LRRC47 ENSDARG00000088335 None Not determined 1
LOC100329589 EPHB1 ENSDARG00000043852 None Not determined 1
LOC100329739 CRY2 ENSDARG00000088549 1 Not determined 3
LOC100330875 GUCY1A2 ENSDARG00000093185 None Not determined 2
LOC100330881 BICD2 ENSDARG00000079184 1 Not determined 1
LOC100332313 MYO3B ENSDARG00000058946 None Not determined 2
LOC100332814 DCLK2 ENSDARG00000079882 None Not determined 1
LOC100333120 ITPKB ENSDARG00000053488 1 Not determined 1
LOC100333183 DTX1 ENSDARG00000062840 1 Not determined 1
LOC100334189 FABP4 ENSDARG00000088621 None Not determined 2
LOC557210 BACH2 ENSDARG00000036569 3 Not determined 14
LOC557383 BICD2 ENSDARG00000075571 3 Normal 1
LOC558824 ADAD2 ENSDARG00000075906 1 Not determined 1
LOC559281 IRS1 ENSDARG00000054087 1 Not determined 7
LOC559395 SLC7A10 ENSDARG00000051730 2 Not determined 1
LOC559806 HTR2A ENSDARG00000058165 None Not determined 2
LOC562441 DCLK2 ENSDARG00000091223 None Not determined 1
LOC564281 C1GALT1 ENSDARG00000074025 None Not determined 2
LOC564785 PLSCR5 ENSDARG00000091266 None Not determined 1
LOC566228 KCNG4 ENSDARG00000051892 4 Not determined 1
LOC566955 ALX3 ENSDARG00000091086 3 Not determined 1
LOC569664 CLSTN2 ENSDARG00000060638 2 Not determined 4
LOC570938 RASAL1 ENSDARG00000041515 None Not determined 1
lpp LPP ENSDARG00000023578 1 Not determined 10
lrrc47 LRRC47 ENSDARG00000053138 None Not determined 1
mgat5 MGAT5 ENSDARG00000071506 6 Not determined 1
mgst1 MGST1 ENSDARG00000032618 None Not determined 1
mipep MIPEP ENSDARG00000055344 None Not determined 3
mpz MPZ ENSDARG00000038609 1 Normal 1
mycbpap MYCBPAP ENSDARG00000069194 2 Not determined 1
ncam2 NCAM2 ENSDARG00000017466 5 Not determined 3
negr1 NEGR1 ENSDARG00000021607 None Not determined 6
NEGR1 (2 of 2) NEGR1 ENSDARG00000091309 None Not determined 6
NP_001004682.1 FABP4 ENSDARG00000017299 None Not determined 2
NP_001017595.1 MAD2L2 ENSDARG00000007096 None Not determined 1
NP_001139235.1 TSHR ENSDARG00000037195 2 Not determined 4
NP_001152755.1 DKK3 ENSDARG00000077630 None Not determined 1
NP_571861.2 CRY2 ENSDARG00000024049 None Not determined 3
nr3c2 NR3C2 ENSDARG00000037025 1 Not determined 5
nsun2 NSUN2 ENSDARG00000056665 3 Not determined 1
ntla T ENSDARG00000009905 1 Not determined 2
ntlb T ENSDARG00000039806 2 Not determined 2
ntm NEGR1 ENSDARG00000018065 None Not determined 6
ntm OPCML ENSDARG00000018065 None Not determined 2
oat SLC22A8 ENSDARG00000055523 None Not determined 1
oatx SLC22A8 ENSDARG00000019713 None Not determined 1
pcdh17 PCDH17 ENSDARG00000027041 2 Not determined 1
pcdh2ac PCDHAC1 ENSDARG00000058875 2 Not determined 1
PCDHAC2 (1 of 2) PCDHAC1 ENSDARG00000092081 None Not determined 1
pcp4l1 PCP4L1 ENSDARG00000023181 None Not determined 1
pdcd6ip PDCD6IP ENSDARG00000025269 2 Not determined 1
pdlim5 PDLIM5 ENSDARG00000038267 2 Not determined 2
PEBP4 PEBP4 ENSDARG00000089900 None Not determined 1
pms1 PMS1 ENSDARG00000000476 None Not determined 2
pom121 POM121 ENSDARG00000055113 1 Not determined 1
pou3f3a POU3F1 ENSDARG00000042032 None Not determined 3
prickle1a PRICKLE1 ENSDARG00000040649 1 Not determined 2
prickle1b PRICKLE1 ENSDARG00000045694 None Not determined 2
psat1 PSAT1 ENSDARG00000016733 None Not determined 2
rh50 RHBG ENSDARG00000041848 1 Not determined 1
rhbg RHBG ENSDARG00000009018 1 Not determined 1
rhov RHOV ENSDARG00000070434 None Not determined 1
rngtt RNGTT ENSDARG00000032261 None Not determined 2
roraa RORA ENSDARG00000031768 1 Not determined 11
rorab RORA ENSDARG00000001910 1 Not determined 11
rorb RORB ENSDARG00000033498 None Not determined 2
rorca RORB ENSDARG00000057231 None Not determined 2
rps14 RPS14 ENSDARG00000036629 1 Not determined 1
rps29 RPS29 ENSDARG00000041232 None Not determined 1
sall3 SALL3 ENSDARG00000079613 None Not determined 2
sdhc SDHC ENSDARG00000038608 None Not determined 1
sertad2 SERTAD2 ENSDARG00000055530 None Not determined 1
si:ch211-130m23.2 ARRDC3 ENSDARG00000095136 1 Not determined 2
si:ch211-191j22.6 QPCTL ENSDARG00000062293 None Not determined 3
si:ch211-234b19.1 EPHB1 ENSDARG00000076757 4 Not determined 1
si:ch211-240j18.3 KSR2 ENSDARG00000094526 None Not determined 3
si:ch211-243k12.1 LUZP2 ENSDARG00000068247 None Not determined 5
si:ch211-247h9.1 CNTN6 ENSDARG00000062880 3 Not determined 3
si:ch211-251m13.1 KCNH5 ENSDARG00000069117 5 Not determined 2
si:ch211-266d19.3 RREB1 ENSDARG00000063701 1 Not determined 6
si:ch211-279l9.6 RREB1 ENSDARG00000042652 3 Not determined 6
si:ch211-51g4.4 SORBS2 ENSDARG00000061603 5 Normal 1
si:ch211-71m22.1 PLSCR5 ENSDARG00000058638 None Not determined 1
si:ch211-71m22.3 PLSCR5 ENSDARG00000079075 None Not determined 1
si:ch211-97m8.1 ITPKB ENSDARG00000010059 None Not determined 1
si:ch73-131e21.6 SERTAD2 ENSDARG00000093412 None Not determined 1
si:ch73-138e16.6 ZNF664 ENSDARG00000074789 1 Not determined 2
si:ch73-138e9.2 TRAK1 ENSDARG00000041304 2 Not determined 1
si:ch73-21k16.4 GPATCH2 ENSDARG00000095429 None Not determined 2
si:dkey-114g7.4 FBXO46 ENSDARG00000043718 2 Not determined 1
si:dkey-119m7.4 SLC22A8 ENSDARG00000071049 4 Normal 1
si:dkey-149j18.2 QPCTL ENSDARG00000061691 None Not determined 3
si:dkey-158a20.2 RORB ENSDARG00000017780 2 Not determined 2
si:dkey-172m14.2 ARRDC3 ENSDARG00000067664 None Not determined 2
si:dkey-172m14.3 ARRDC3 ENSDARG00000052690 1 Not determined 2
si:dkey-177p2.6 SERTAD2 ENSDARG00000042322 2 Not determined 1
si:dkey-195c14.1 SALL3 ENSDARG00000057586 None Not determined 2
si:dkey-202e17.1 C1GALT1 ENSDARG00000062278 None Not determined 2
si:dkey-23c22.2 MAD2L2 ENSDARG00000042456 None Not determined 1
si:dkey-246g23.3 KCNG4 ENSDARG00000062967 2 Normal 1
si:dkey-26c10.6 EPHB1 ENSDARG00000057729 None Not determined 1
si:dkey-29b22.6 SLC6A17 ENSDARG00000007129 1 Not determined 1
si:dkey-4c23.7 CADM2 ENSDARG00000062633 1 Not determined 3
si:dkey-61p9.6 HSPA12B ENSDARG00000068869 3 Not determined 1
si:dkeyp-55c8.1 CLSTN2 ENSDARG00000060637 2 Not determined 4
si:dkeyp-86b9.1 DNAH10 ENSDARG00000061486 4 Not determined 2
slc35c1 SLC35C1 ENSDARG00000091153 None Not determined 1
SLC39A11 SLC39A11 ENSDARG00000089127 None Not determined 4
slc6a17 SLC6A17 ENSDARG00000068787 1 Not determined 1
slc7a10 SLC7A10 ENSDARG00000008100 2 Not determined 1
smad6a SMAD6 ENSDARG00000053209 None Not determined 1
smad6b SMAD6 ENSDARG00000031763 1 Not determined 1
snrpd2 SNRPD2 ENSDARG00000040440 None Not determined 1
snx10a SNX10 ENSDARG00000004405 None Not determined 1
snx10b SNX10 ENSDARG00000040474 1 Not determined 1
sorbs2a SORBS2 ENSDARG00000003046 1 Normal 1
spint1a SPINT1 ENSDARG00000023673 None Not determined 1
spint1b SPINT1 ENSDARG00000012467 2 Not determined 1
srd5a1 SRD5A1 ENSDARG00000020509 None Not determined 2
stc1 STC1 ENSDARG00000003303 1 Not determined 3
stc1l STC1 ENSDARG00000058476 None Not determined 3
STXBP6 (1 of 2) STXBP6 ENSDARG00000088862 1 Not determined 3
stxbp6l STXBP6 ENSDARG00000028354 1 Not determined 3
sucla2 SUCLA2 ENSDARG00000005359 1 Not determined 2
taf4b TAF4B ENSDARG00000075732 1 Not determined 1
tal2 TAL2 ENSDARG00000042041 None Not determined 3
tank TANK ENSDARG00000090402 None Not determined 5
TANK (1 of 2) TANK ENSDARG00000067723 None Not determined 5
tbc1d23 TBC1D23 ENSDARG00000044357 2 Not determined 1
tbx5a TBX5 ENSDARG00000024894 None Not determined 10
tbx5b TBX5 ENSDARG00000092060 None Not determined 10
thnsl2 THNSL2 ENSDARG00000032584 None Not determined 1
THSD7B (2 of 2) THSD7B ENSDARG00000061497 2 Not determined 3
thsd7ba THSD7B ENSDARG00000095022 2 Not determined 3
TMEM38B TMEM38B ENSDARG00000041562 None Not determined 5
tnfrsf19 TNFRSF19 ENSDARG00000041869 3 Not determined 3
tox TOX ENSDARG00000032317 2 Not determined 3
tp73 TP73 ENSDARG00000017953 None Not determined 1
tram1 TRAM1L1 ENSDARG00000019137 None Not determined 2
tyw3 TYW3 ENSDARG00000038222 None Not determined 2
vps18 VPS18 ENSDARG00000070433 1 Not determined 1
wu:fe36b12 PLSCR5 ENSDARG00000077468 2 Not determined 1
wu:fo94f09 ZFP64 ENSDARG00000061147 None Not determined 2
zgc:101814 C3orf26 ENSDARG00000004727 None Not determined 1
zgc:110353 ARRDC3 ENSDARG00000039443 1 Not determined 2
zgc:110626 ARRDC3 ENSDARG00000053159 3 Not determined 2
zgc:110848 LYPLAL1 ENSDARG00000088764 None Not determined 6
zgc:113278 TRAM1L1 ENSDARG00000037813 1 Not determined 2
zgc:136739 BACH1 ENSDARG00000062553 None Not determined 2
zgc:152904 NCAM2 ENSDARG00000055669 1 Not determined 3
zgc:153573 CNTN6 ENSDARG00000019405 1 Not determined 3
zgc:158346 FBXL7 ENSDARG00000062251 None Not determined 3
zgc:158420 ZDHHC21 ENSDARG00000079660 None Not determined 2
zgc:158671 WFDC1 ENSDARG00000058003 2 Not determined 1
zgc:162200 BICD2 ENSDARG00000079934 1 Not determined 1
zgc:162925 SLC6A17 ENSDARG00000037422 1 Not determined 1
zgc:165670 LHPP ENSDARG00000060196 None Not determined 3
zgc:171629 GPC6 ENSDARG00000091739 None Not determined 9
zgc:56116 PDLIM5 ENSDARG00000027600 1 Not determined 2
zgc:56306 IRS1 ENSDARG00000037099 1 Not determined 7
zgc:56596 UBL4B ENSDARG00000007359 None Not determined 1
zgc:92034 ARRDC3 ENSDARG00000036028 None Not determined 2
zgc:92279 EYA2 ENSDARG00000018984 2 Not determined 2
zgc:92357 MGST1 ENSDARG00000022165 None Not determined 1
zgc:92901 OPCML ENSDARG00000013005 1 Not determined 2
ZNF608 ZNF608 ENSDARG00000075823 2 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • A2BP1
  • BRWD2
  • C1orf182
  • C1orf61
  • C6orf10
  • C6orf118
  • CCDC100
  • CCDC27
  • CCDC27
  • CCDC27
  • CNTNAP2
  • CYP2E1
  • DAOA
  • DTWD2
  • FAM81A
  • FCMD
  • FLJ45831
  • GRM7
  • HCP5
  • HLA-B
  • HMP19
  • KIAA0495
  • KIAA0495
  • KIAA0495
  • KIAA0999
  • LOC129607
  • LOC129607
  • LOC131149
  • LOC400451
  • LOC642502
  • LOC646486
  • LOC92017
  • OAS2
  • QPTCL
  • RAD51AP2
  • RANBP17
  • TAF1C
  • TCBA1
  • TLE1
  • TLE1
  • TUSC1
  • UNQ194
  • WDR49
  • ZFAT1
  • ZNF484
* quick link - http://q.sanger.ac.uk/grepzgjj