GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abhd3 ABHD3 ENSDARG00000018809 None Not determined 1
agpat2 AGPAT1 ENSDARG00000068437 None Not determined 1
alg1 ALG1 ENSDARG00000054963 None Not determined 1
alg14 ALG14 ENSDARG00000039671 1 Not determined 2
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
cdh8 CDH8 ENSDARG00000037478 2 Not determined 3
cntnap2 CNTNAP4 ENSDARG00000074558 None Not determined 3
dlg2 DLG2 ENSDARG00000076691 2 Not determined 5
elovl2 ELOVL2 ENSDARG00000045414 None Not determined 4
fads2 FADS2 ENSDARG00000019532 None Not determined 15
KCNH7 (2 of 2) KCNH7 ENSDARG00000062687 3 Not determined 1
KCNH7 (1 of 2) KCNH7 ENSDARG00000076281 None Not determined 1
klf12a KLF12 ENSDARG00000015312 1 Not determined 3
klf12b KLF12 ENSDARG00000032197 None Not determined 3
klf3 KLF12 ENSDARG00000015495 1 Not determined 3
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
LOC100007362 PCDH20 ENSDARG00000036424 None Not determined 4
LOC100330155 LASS4 ENSDARG00000018619 3 Normal 2
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100334409 CNTNAP4 ENSDARG00000074351 None Not determined 3
LOC556439 SGPP1 ENSDARG00000079369 None Not determined 2
LOC559157 CNTNAP4 ENSDARG00000058969 1 Not determined 3
papd7 PAPD7 ENSDARG00000062114 2 Not determined 1
PAQR9 PAQR9 ENSDARG00000052059 None Not determined 1
pdxdc1 PDXDC1 ENSDARG00000007549 None Not determined 4
pkd2l1 PKD2L1 ENSDARG00000022503 2 Not determined 3
pld2 PLD2 ENSDARG00000034262 None Not determined 1
plekhh1 PLEKHH1 ENSDARG00000053835 5 Not determined 1
Q5RHX9_DANRE CDK17 ENSDARG00000079470 2 Not determined 1
si:ch211-122m3.1 CNTNAP4 ENSDARG00000067824 5 Not determined 3
si:ch211-168k14.2 PLD2 ENSDARG00000056191 3 1 phenotype 1
si:ch211-188i4.3 SGPP1 ENSDARG00000060534 1 Not determined 2
si:dkey-20i10.6 ATP10D ENSDARG00000078887 3 Not determined 2
si:dkey-246k9.1 SPTLC3 ENSDARG00000030743 None Not determined 4
si:dkey-27i16.3 PCDH20 ENSDARG00000057773 5 Not determined 4
si:dkey-7f3.15 APOA5 ENSDARG00000094929 None Not determined 22
syt9a SYT9 ENSDARG00000003994 2 Not determined 1
syt9b SYT9 ENSDARG00000029239 2 Not determined 1
trh1 LASS4 ENSDARG00000031387 2 Not determined 2
zgc:101053 LPAR2 ENSDARG00000042338 1 Not determined 1
zgc:112263 ELOVL2 ENSDARG00000057365 None Not determined 4
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:123246 LPAR2 ENSDARG00000042561 1 Not determined 1
zgc:153394 ELOVL2 ENSDARG00000068551 1 Not determined 4
zgc:162985 ILKAP ENSDARG00000040615 None Not determined 1
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOE-C1
  • APOE-C2
  • APOE-C4
  • FADS1
  • FADS1
  • FADS3
  • FADS3
  • ITGA9
  • OR812
  • PNLIPRP2
  • ZNF600
* quick link - http://q.sanger.ac.uk/s8eibjtp