GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genetic determinants of statin-induced low-density lipoprotein cholesterol reduction: the Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating Rosuvastatin (JUPITER) trial.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcg2a ABCG2 ENSDARG00000043037 None Not determined 10
abcg2b ABCG2 ENSDARG00000079361 None Not determined 10
abcg2c ABCG2 ENSDARG00000058574 3 Not determined 10
abcg2d ABCG2 ENSDARG00000016818 1 Not determined 10
apoeb APOE ENSDARG00000040295 None Not determined 42
EPB41L2 EPB41L2 ENSDARG00000060497 2 Not determined 2
gmpr GMPR ENSDARG00000016160 None Not determined 4
LOC100332111 SHC3 ENSDARG00000057731 2 Not determined 1
LOC100332187 S1PR3 ENSDARG00000087622 1 Not determined 1
mylipa MYLIP ENSDARG00000008859 None Not determined 3
mylipb MYLIP ENSDARG00000055118 None Not determined 3
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
plg LPA ENSDARG00000023111 2 Not determined 10
s1pr3 S1PR3 ENSDARG00000042470 None Not determined 1
si:ch211-119o8.6 ZNF98 ENSDARG00000026972 1 Not determined 3
zgc:110064 APOE ENSDARG00000086370 None Not determined 42

The following reported genes could not be linked automatically to a zebrafish gene:

  • C9orf47
  • IDOL
  • LOC342994
* quick link - http://q.sanger.ac.uk/c6gdmja2