GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A8WFQ6_DANRE SLC25A1 ENSDARG00000076381 None Not determined 2
abca1a ABCA1 ENSDARG00000074635 9 Not determined 13
angptl3 ANGPTL3 ENSDARG00000044365 None Not determined 7
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa4 APOA4 ENSDARG00000040298 1 Not determined 11
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
apoa4 APOA1 ENSDARG00000040298 1 Not determined 13
apoeb APOE ENSDARG00000040295 None Not determined 42
cetp CETP ENSDARG00000030872 1 Not determined 27
fads2 FADS2 ENSDARG00000019532 None Not determined 15
gc ALB ENSDARG00000089310 None Not determined 1
gls2 GLS2 ENSDARG00000069095 1 Not determined 3
ldlr LDLR ENSDARG00000029476 1 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
lipg LIPG ENSDARG00000031044 1 Not determined 9
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100334818 SLC2A4 ENSDARG00000001937 None Not determined 2
LOC562087 PPM1K ENSDARG00000076011 4 Normal 3
LOC797748 GLS2 ENSDARG00000062781 None Not determined 3
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 None Not determined 21
MR1BB_DANRE MTNR1B ENSDARG00000086493 None Not determined 15
mtnr1ba MTNR1B ENSDARG00000053833 None Not determined 15
mtnr1bb MTNR1B ENSDARG00000086883 None Not determined 15
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
pltp PLTP ENSDARG00000035768 1 Not determined 5
PP1RB_DANRE PPP1R11 ENSDARG00000036063 None Not determined 1
ppm1k PPM1K ENSDARG00000010655 None Not determined 3
si:ch1073-189o9.1 MLXIPL ENSDARG00000089107 None Not determined 13
si:ch211-236l14.3 CPT1A ENSDARG00000062054 3 Not determined 2
si:dkey-102c8.6 GLS2 ENSDARG00000002917 None Not determined 3
si:dkey-178e17.1 SLC25A1 ENSDARG00000080000 None Not determined 2
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-56p7.8 CPT1A ENSDARG00000059770 1 Not determined 2
si:dkey-7f3.15 APOA5 ENSDARG00000094929 None Not determined 22
si:dkey-7f3.15 APOA1 ENSDARG00000094929 None Not determined 13
si:dkey-7f3.15 APOA4 ENSDARG00000094929 None Not determined 11
slc16a10 SLC16A10 ENSDARG00000020984 None Not determined 2
SLC16A10 (2 of 2) SLC16A10 ENSDARG00000089969 None Not determined 2
slc1a4 SLC1A4 ENSDARG00000000551 2 Not determined 2
slc25a1 SLC25A1 ENSDARG00000057110 2 Not determined 2
tat TAT ENSDARG00000069630 2 Not determined 2
zgc:110064 APOE ENSDARG00000086370 None Not determined 42
zgc:112484 CPT1A ENSDARG00000037943 1 Not determined 2
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:171581 ABCA1 ENSDARG00000079009 5 Not determined 13
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:77082 DHDPSL ENSDARG00000018944 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC1
  • APOC2
  • APOC3
  • C20:2
  • C20:3
  • F12
  • FADS1
  • FADS3
  • FCGR2A
  • FCGR2B
  • G6PC2
  • KLKB1
  • PDXC1
* quick link - http://q.sanger.ac.uk/llt9wqq3