GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analysis of age-at-onset in Alzheimer's disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
adamts9 ADAMTS9 ENSDARG00000077778 5 Not determined 5
ALPK3 (2 of 2) ALPK3 ENSDARG00000090375 3 Not determined 1
apoeb APOE ENSDARG00000040295 None Not determined 42
LOC560512 PVRL2 ENSDARG00000077419 None Not determined 9
LOC560816 PVRL2 ENSDARG00000062831 1 Not determined 9
pvrl2l PVRL2 ENSDARG00000063390 1 Not determined 9
pvrl4 PVRL2 ENSDARG00000094356 None Not determined 9
rnft2 RNFT2 ENSDARG00000053019 1 Not determined 2
si:ch211-12e13.7 KCNV2 ENSDARG00000062906 None Not determined 3
si:ch211-141e20.2 PVRL2 ENSDARG00000093349 None Not determined 9
si:ch211-214p13.3 PVRL2 ENSDARG00000087403 1 Not determined 9
si:ch211-222f23.6 PVRL2 ENSDARG00000042880 None Not determined 9
si:ch211-241o7.4 KCNV2 ENSDARG00000076644 None Not determined 3
si:dkey-24l11.1 SLC28A1 ENSDARG00000060879 3 Not determined 1
si:dkey-258f14.3 VLDLR ENSDARG00000075974 None Not determined 3
si:dkey-281i8.1 PVRL2 ENSDARG00000069936 None Not determined 9
si:dkey-77f17.3 ALPK3 ENSDARG00000078989 3 Normal 1
si:rp71-39b20.4 KCNV2 ENSDARG00000035861 1 Not determined 3
tomm40 TOMM40 ENSDARG00000092112 1 Not determined 23
tomm40l TOMM40 ENSDARG00000036721 None Not determined 23
vldlr VLDLR ENSDARG00000006257 3 Not determined 3
zgc:110064 APOE ENSDARG00000086370 None Not determined 42
znf592 ZNF592 ENSDARG00000060885 1 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC1
  • DCHS2
  • HRK
  • LEMD2
  • LOC390958
  • MIR1275
  • MLN
  • Sec11C
* quick link - http://q.sanger.ac.uk/hme8paxt