GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
alas1 ALAS1 ENSDARG00000021059 1 Not determined 1
ANK3 (2 of 2) ANK3 ENSDARG00000061736 10 Not determined 6
bap1 BAP1 ENSDARG00000063051 3 Not determined 1
bbs1 BBS1 ENSDARG00000075169 2 Not determined 1
brms1 BRMS1 ENSDARG00000051955 2 Not determined 1
cnih2 CNIH2 ENSDARG00000043662 None Not determined 1
cnnm4 CNNM4 ENSDARG00000074309 1 Not determined 1
ctsf CTSF ENSDARG00000063095 2 Not determined 1
ddx23 DDX23 ENSDARG00000021945 None Not determined 1
dnah1 DNAH1 ENSDARG00000055736 1 Not determined 1
dpp3 DPP3 ENSDARG00000020676 1 Not determined 1
FAM83E FAM83E ENSDARG00000089489 None Not determined 1
fgf21 FGF21 ENSDARG00000070492 1 Not determined 3
glt8d1 GLT8D1 ENSDARG00000040157 2 Not determined 2
gnl3 GNL3 ENSDARG00000006219 None Not determined 4
LMAN2L (2 of 2) LMAN2L ENSDARG00000018865 None Not determined 2
lman2lb LMAN2L ENSDARG00000088663 None Not determined 2
LOC100150844 PRKCD ENSDARG00000070651 3 Not determined 3
LOC100151130 RASIP1 ENSDARG00000074829 None Not determined 4
LOC100329768 GPR20 ENSDARG00000074826 None Not determined 1
LOC100329789 CNNM4 ENSDARG00000077508 2 Not determined 1
LOC100330824 GAL3ST3 ENSDARG00000073728 2 Not determined 1
LOC100333421 LRFN4 ENSDARG00000039500 2 Not determined 1
LOC100334018 SLC29A2 ENSDARG00000033909 1 Not determined 1
LOC100334245 PELI3 ENSDARG00000003041 None Not determined 1
LOC559807 MUSTN1 ENSDARG00000054026 None Not determined 2
LOC559873 RFT1 ENSDARG00000060398 None Not determined 2
LOC564450 B3GNT1 ENSDARG00000077583 None Not determined 1
LOC564761 ITIH3 ENSDARG00000055053 5 Not determined 4
LOC564761 ITIH1 ENSDARG00000055053 5 Not determined 2
LOC794428 GPR20 ENSDARG00000077427 1 Not determined 1
lygl1 LYG1 ENSDARG00000056874 None Not determined 1
lygl1 LYG2 ENSDARG00000056874 None Not determined 1
mad1l1 MAD1L1 ENSDARG00000033852 3 Not determined 3
mgat4a MGAT4A ENSDARG00000063330 2 Not determined 2
mitd1 MITD1 ENSDARG00000044766 None Not determined 1
mrpl11 MRPL11 ENSDARG00000013075 1 Not determined 1
nek4 NEK4 ENSDARG00000040152 3 Not determined 2
npas4 NPAS4 ENSDARG00000055752 2 Normal 1
NPAS4 (2 of 3) NPAS4 ENSDARG00000061920 None Not determined 1
NP_001002324.1 ZDHHC24 ENSDARG00000036364 None Not determined 1
NP_001020335.1 ITIH4 ENSDARG00000024928 None Not determined 4
NP_001093459.1 SPTBN2 ENSDARG00000053956 3 Not determined 1
NP_001183982.1 MUSTN1 ENSDARG00000089086 None Not determined 2
nt5dc2 NT5DC2 ENSDARG00000059646 2 Not determined 1
NTN5 NTN5 ENSDARG00000036422 3 Not determined 1
odz4 ODZ4 ENSDARG00000034264 5 Not determined 4
pacs1 PACS1 ENSDARG00000044556 None Not determined 1
PACS1 (3 of 3) PACS1 ENSDARG00000075246 1 Not determined 1
PACS1 (1 of 3) PACS1 ENSDARG00000019800 1 Not determined 1
PBRM1 (1 of 2) PBRM1 ENSDARG00000003877 3 Normal 3
pbrm1l PBRM1 ENSDARG00000077038 2 Not determined 3
pc PC ENSDARG00000051939 2 Not determined 2
pcl PC ENSDARG00000000972 2 Not determined 2
peli1 PELI3 ENSDARG00000044083 1 Not determined 1
peli2 PELI3 ENSDARG00000029045 1 Not determined 1
PELI3 PELI3 ENSDARG00000087452 1 Not determined 1
prkcd PRKCD ENSDARG00000009208 1 Not determined 3
Q5RHP7_DANRE SYNE1 ENSDARG00000009499 18 2 normal 5
rbm4.1 RBM4B ENSDARG00000036386 2 Normal 1
rbm4.1 RBM4 ENSDARG00000036386 2 Normal 1
rbm4.2 RBM4B ENSDARG00000055080 1 Not determined 1
rbm4.2 RBM4 ENSDARG00000055080 1 Not determined 1
rbm4.3 RBM4B ENSDARG00000022129 2 Not determined 1
rbm4.3 RBM4 ENSDARG00000022129 2 Not determined 1
RCE1 RCE1 ENSDARG00000077909 None Not determined 1
RIN1 (2 of 2) RIN1 ENSDARG00000070100 None Not determined 1
rnd1 RND1 ENSDARG00000030547 1 Not determined 1
rnd1l RND1 ENSDARG00000004218 None Not determined 1
sema3bl SEMA3G ENSDARG00000007560 3 Not determined 1
sema3h SEMA3G ENSDARG00000042616 3 Not determined 1
SFMBT1 SFMBT1 ENSDARG00000044915 1 Not determined 2
si:ch1073-288d12.1 NISCH ENSDARG00000094828 None Not determined 2
si:ch211-103f16.1 NISCH ENSDARG00000043077 None Not determined 2
si:ch211-121j5.4 C2orf55 ENSDARG00000092835 1 Not determined 1
si:ch211-123o7.5 CD248 ENSDARG00000077938 None Not determined 1
si:ch211-126j24.1 PACS1 ENSDARG00000074724 None Not determined 1
si:ch211-126j24.1 PACS1 ENSDARG00000075088 None Not determined 1
si:ch211-149l1.2 C2orf55 ENSDARG00000079501 2 Not determined 1
si:ch211-250a23.3 LRFN4 ENSDARG00000055132 None Not determined 1
si:ch211-254d18.3 EIF5B ENSDARG00000016548 None Not determined 1
si:ch211-255a21.3 CNNM4 ENSDARG00000092541 1 Not determined 1
si:ch211-266a5.1 CCDC87 ENSDARG00000045683 3 Not determined 1
si:ch73-131e21.5 RAB1B ENSDARG00000052263 None Not determined 1
si:dkey-109n11.1 DBP ENSDARG00000063014 2 Not determined 2
si:dkey-17e16.11 NPAS4 ENSDARG00000087753 None Not determined 1
si:dkey-17e16.14 TMEM151A ENSDARG00000079908 None Not determined 1
si:dkey-197a18.7 RIN1 ENSDARG00000079095 None Not determined 1
si:dkey-40m6.13 SPHK2 ENSDARG00000069893 None Not determined 2
si:dkey-46d17.3 LRFN4 ENSDARG00000078078 2 Not determined 1
si:dkey-57a22.7 REV1 ENSDARG00000018296 2 Not determined 1
si:dkeyp-36h11.3 RCE1 ENSDARG00000088207 None Not determined 1
si:dkeyp-69b9.5 DBP ENSDARG00000057652 4 Normal 2
SLC29A2 (1 of 3) SLC29A2 ENSDARG00000088521 None Not determined 1
spcs1 SPCS1 ENSDARG00000059298 None Not determined 1
stab1l STAB1 ENSDARG00000076484 7 Normal 2
SYNE1 (1 of 2) SYNE1 ENSDARG00000063068 22 Not determined 5
syt12 SYT12 ENSDARG00000063135 None Not determined 1
tlr9 TLR9 ENSDARG00000044490 3 Normal 1
tmem110 TMEM110 ENSDARG00000013694 None Not determined 2
TMEM151A (1 of 2) TMEM151A ENSDARG00000077986 2 Not determined 1
tnfaip6 STAB1 ENSDARG00000093440 1 Not determined 2
tnnc1a TNNC1 ENSDARG00000011400 3 Not determined 1
tnnc1b TNNC1 ENSDARG00000037539 None Not determined 1
twf1l TWF2 ENSDARG00000094792 1 Not determined 1
txndc9 TXNDC9 ENSDARG00000069853 2 Not determined 1
wdr82 WDR82 ENSDARG00000014083 2 1 phenotype 1
zdhhc24 ZDHHC24 ENSDARG00000078877 None Not determined 1
zgc:110377 ITIH1 ENSDARG00000055036 1 Not determined 2
zgc:110377 ITIH3 ENSDARG00000055036 1 Not determined 4
zgc:110527 SLC29A2 ENSDARG00000001767 1 Not determined 1
zgc:110682 RBM14 ENSDARG00000012723 1 Not determined 1
zgc:112089 C2orf15 ENSDARG00000069850 None Not determined 1
zgc:112089 MRPL30 ENSDARG00000069850 None Not determined 1
zgc:112092 TWF2 ENSDARG00000009727 None Not determined 1
zgc:112427 CCS ENSDARG00000092003 1 Not determined 1
zgc:136773 SF3B2 ENSDARG00000018049 1 Not determined 1
zgc:152851 LIPT1 ENSDARG00000025233 2 Not determined 1
zgc:152952 TSGA10 ENSDARG00000052512 None Not determined 1
zgc:153346 GLYCTK ENSDARG00000060120 2 Not determined 1
zgc:162288 KLC2 ENSDARG00000075485 None Not determined 1
zgc:162651 CD248 ENSDARG00000079898 None Not determined 1
zgc:162941 LYG2 ENSDARG00000071701 None Not determined 1
zgc:162941 LYG1 ENSDARG00000071701 None Not determined 1
zgc:171763 ANK3 ENSDARG00000077582 6 Not determined 6
zgc:172282 LRFN4 ENSDARG00000075231 None Not determined 1
zgc:195212 C11orf80 ENSDARG00000075203 None Not determined 1
zgc:73136 YIF1A ENSDARG00000019636 None Not determined 1
zgc:77262 RBM4 ENSDARG00000044545 None Not determined 1
zgc:77262 RBM4B ENSDARG00000044545 None Not determined 1
zgc:77262 RBM14 ENSDARG00000044545 None Not determined 1
zgc:85696 RBM14 ENSDARG00000001285 None Not determined 1
zgc:92872 RPL18 ENSDARG00000029533 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • ACTN3
  • C11orf86
  • C15orf53
  • CA11
  • CANCNA1C
  • CANCNB3
  • FER1L5
  • FUT1
  • FUT2
  • IZUMO1
  • LBA1
  • LOC440957
  • LOC731779
  • MAMSTR
  • PHF7
  • PPM1M
  • SEC1
  • SNORD19
  • SNORD19B
  • SNORD69
* quick link - http://q.sanger.ac.uk/adhffy07