GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Human metabolic individuality in biomedical and pharmaceutical research.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
acadm ACADM ENSDARG00000038900 3 Not determined 2
acads ACADS ENSDARG00000030781 None Not determined 2
ahr1a AHR ENSDARG00000020046 3 Not determined 3
ahr1b AHR ENSDARG00000023537 1 Not determined 3
ahr2 AHR ENSDARG00000021833 3 Not determined 3
alp ALPL ENSDARG00000015546 None Not determined 6
cyp3a65 CYP3A4 ENSDARG00000045627 1 Not determined 1
cyp3c1 CYP3A4 ENSDARG00000015575 1 Not determined 1
cyp3c1l2 CYP3A4 ENSDARG00000037873 None Not determined 1
elovl2 ELOVL2 ENSDARG00000045414 None Not determined 4
enpep ENPEP ENSDARG00000057064 4 Not determined 3
etfdh ETFDH ENSDARG00000038834 None Not determined 2
gls2 GLS2 ENSDARG00000069095 1 Not determined 3
ivd IVD ENSDARG00000042853 2 Not determined 1
lactb LACTB ENSDARG00000040803 1 Not determined 2
LOC100000685 SLC22A4 ENSDARG00000068603 2 Not determined 5
LOC100002956 NAT8 ENSDARG00000078991 None Not determined 5
LOC100004652 NAT8 ENSDARG00000077028 None Not determined 5
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC100333321 PRODH ENSDARG00000044804 2 Normal 1
LOC794381 NAT2 ENSDARG00000036066 None Not determined 4
LOC795256 NAT2 ENSDARG00000036067 None Not determined 4
LOC797748 GLS2 ENSDARG00000062781 None Not determined 3
NP_001107902.1 SLC2A9 ENSDARG00000063288 3 1 phenotype 14
nt5e NT5E ENSDARG00000071017 1 Not determined 1
OPLAH OPLAH ENSDARG00000045123 3 Not determined 1
pdxdc1 PDXDC1 ENSDARG00000007549 None Not determined 4
phgdh PHGDH ENSDARG00000001873 2 Not determined 2
PRODH (3 of 3) PRODH ENSDARG00000086512 1 Not determined 1
PRODH (2 of 3) PRODH ENSDARG00000086746 None Not determined 1
scd SCD ENSDARG00000033662 1 Not determined 1
scdb SCD ENSDARG00000030265 None Not determined 1
si:ch1073-409b12.4 SLC22A4 ENSDARG00000094112 None Not determined 5
si:dkey-102c8.6 GLS2 ENSDARG00000002917 None Not determined 3
si:dkey-21n8.3 CYP3A4 ENSDARG00000037874 None Not determined 1
si:dkey-225d17.3 CPS1 ENSDARG00000020028 3 Not determined 6
si:dkeyp-120h9.1 SLC7A6 ENSDARG00000020278 1 Not determined 1
si:rp71-1f1.4 NAT2 ENSDARG00000092476 None Not determined 4
si:rp71-1f1.5 NAT2 ENSDARG00000091672 None Not determined 4
si:rp71-1f1.6 NAT2 ENSDARG00000089278 None Not determined 4
slc16a10 SLC16A10 ENSDARG00000020984 None Not determined 2
SLC16A10 (2 of 2) SLC16A10 ENSDARG00000089969 None Not determined 2
slc16a9a SLC16A9 ENSDARG00000013926 1 Not determined 3
slc16a9b SLC16A9 ENSDARG00000005947 2 Not determined 3
slc22a4 SLC22A4 ENSDARG00000005335 2 Not determined 5
slc2a11b SLC2A9 ENSDARG00000093395 2 1 phenotype 14
slc2a15a SLC2A9 ENSDARG00000029894 None Not determined 14
slc2a15b SLC2A9 ENSDARG00000053269 1 Not determined 14
slc7a6 SLC7A6 ENSDARG00000054423 2 Normal 1
slco1d1 SLCO1B1 ENSDARG00000060181 None Not determined 7
wu:fb81h03 ACE ENSDARG00000079166 4 Not determined 3
zgc:101040 NAT2 ENSDARG00000005176 None Not determined 4
zgc:103601 NAT2 ENSDARG00000036068 1 Not determined 4
zgc:112263 ELOVL2 ENSDARG00000057365 None Not determined 4
zgc:153269 CYP3A4 ENSDARG00000070021 2 Not determined 1
zgc:153394 ELOVL2 ENSDARG00000068551 1 Not determined 4
zgc:162420 HPS5 ENSDARG00000071062 1 Not determined 2
zgc:64076 SLC22A1 ENSDARG00000030530 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABO
  • AKR1C
  • CYP4A
  • FADS1
  • FUT2
  • KLKB1
  • UGT1A
* quick link - http://q.sanger.ac.uk/57haonjy