GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
aire AIRE ENSDARG00000056784 2 Normal 1
LOC570106 PFKL ENSDARG00000060504 2 Not determined 1
zgc:110298 PFKL ENSDARG00000042375 None Not determined 1
zgc:66317 PADI4 ENSDARG00000044167 2 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • HLA locus
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