GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ahr1a AHR ENSDARG00000020046 3 Not determined 3
ahr1b AHR ENSDARG00000023537 1 Not determined 3
ahr2 AHR ENSDARG00000021833 3 Not determined 3
cox5aa COX5A ENSDARG00000088383 None Not determined 1
cox5ab COX5A ENSDARG00000018119 None Not determined 1
cplx3a CPLX3 ENSDARG00000062508 None Not determined 3
cplx3b CPLX3 ENSDARG00000089486 None Not determined 3
CSK (2 of 2) CSK ENSDARG00000067996 None Not determined 4
cyp1a CYP1A2 ENSDARG00000026039 2 Not determined 4
cyp1a CYP1A1 ENSDARG00000026039 2 Not determined 5
cyp1d1 CYP1A1 ENSDARG00000035569 None Not determined 5
cyp1d1 CYP1A2 ENSDARG00000035569 None Not determined 4
edc3 EDC3 ENSDARG00000051931 2 Not determined 1
LOC100004357 SCAMP5 ENSDARG00000040274 None Not determined 1
NP_001019574.1 COX5A ENSDARG00000017906 None Not determined 1
NP_001071067.1 CSK ENSDARG00000070805 None Not determined 4
NP_001165054.1 CPLX3 ENSDARG00000091510 None Not determined 3
ppcdc PPCDC ENSDARG00000033020 None Not determined 1
scamp2 SCAMP2 ENSDARG00000010279 None Not determined 1
scamp2l SCAMP2 ENSDARG00000017010 1 Not determined 1
scamp5 SCAMP5 ENSDARG00000018743 None Not determined 1
ULK3 ULK3 ENSDARG00000075200 1 Not determined 4

The following reported genes could not be linked automatically to a zebrafish gene:

  • C14orf17
  • LMAN1L
  • LMAN1L
  • MP1
* quick link - http://q.sanger.ac.uk/t48sp1yn