GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies susceptibility loci for IgA nephropathy.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abcb3l1 TAP2 ENSDARG00000036787 2 Normal 3
cfh CFHR4 ENSDARG00000075761 1 Not determined 3
cfh CFHR5 ENSDARG00000075761 1 Not determined 2
cfh CFH ENSDARG00000075761 1 Not determined 12
cfh CFHR3 ENSDARG00000075761 1 Not determined 4
cfh CFHR1 ENSDARG00000075761 1 Not determined 2
cfhl1 CFHR4 ENSDARG00000056771 None Not determined 3
cfhl1 CFHR5 ENSDARG00000056771 None Not determined 2
cfhl1 CFH ENSDARG00000056771 None Not determined 12
cfhl1 CFHR3 ENSDARG00000056771 None Not determined 4
cfhl1 CFHR1 ENSDARG00000056771 None Not determined 2
cfhl2 CFHR4 ENSDARG00000056778 3 Not determined 3
cfhl2 CFHR5 ENSDARG00000056778 3 Not determined 2
cfhl2 CFH ENSDARG00000056778 3 Not determined 12
cfhl2 CFHR3 ENSDARG00000056778 3 Not determined 4
cfhl2 CFHR1 ENSDARG00000056778 3 Not determined 2
cfhl3 CFHR4 ENSDARG00000094661 None Not determined 3
cfhl3 CFHR5 ENSDARG00000094661 None Not determined 2
cfhl3 CFH ENSDARG00000094661 None Not determined 12
cfhl3 CFHR3 ENSDARG00000094661 None Not determined 4
cfhl3 CFHR1 ENSDARG00000094661 None Not determined 2
cfhl4 CFHR4 ENSDARG00000094496 None Not determined 3
cfhl4 CFHR5 ENSDARG00000094496 None Not determined 2
cfhl4 CFH ENSDARG00000094496 None Not determined 12
cfhl4 CFHR3 ENSDARG00000094496 None Not determined 4
cfhl4 CFHR1 ENSDARG00000094496 None Not determined 2
LOC100333303 TAP1 ENSDARG00000079766 None Not determined 1
LOC100333801 MTMR3 ENSDARG00000089046 3 Not determined 6
LOC556826 TAP2 ENSDARG00000033446 3 Not determined 3
mhc2dab HLA-DPB1 ENSDARG00000079105 None Not determined 7
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
mhc2dab HLA-DPB2 ENSDARG00000079105 None Not determined 2
mhc2dab HLA-DQB1 ENSDARG00000079105 None Not determined 24
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
NP_001091732.1 HLA-DPB2 ENSDARG00000071168 1 Not determined 2
NP_001091732.1 HLA-DQB1 ENSDARG00000071168 1 Not determined 24
NP_001091732.1 HLA-DPB1 ENSDARG00000071168 1 Not determined 7
psmb11 PSMB9 ENSDARG00000031885 None Not determined 3
psmb8 PSMB8 ENSDARG00000001303 1 Not determined 1
psmb9a PSMB9 ENSDARG00000000656 None Not determined 3
Q5RI69_DANRE CFHR4 ENSDARG00000094134 None Not determined 3
Q5RI69_DANRE CFHR5 ENSDARG00000094134 None Not determined 2
Q5RI69_DANRE CFH ENSDARG00000094134 None Not determined 12
Q5RI69_DANRE CFHR3 ENSDARG00000094134 None Not determined 4
Q5RI69_DANRE CFHR1 ENSDARG00000094134 None Not determined 2
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-104n07.3 HLA-DPB2 ENSDARG00000074510 1 Normal 2
si:busm1-104n07.3 HLA-DQB1 ENSDARG00000074510 1 Normal 24
si:busm1-104n07.3 HLA-DPB1 ENSDARG00000074510 1 Normal 7
si:busm1-160c18.1 HLA-DQA1 ENSDARG00000053739 None Not determined 27
si:busm1-160c18.1 HLA-DPA1 ENSDARG00000053739 None Not determined 4
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DPB2 ENSDARG00000053738 None Not determined 2
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000053738 None Not determined 24
si:busm1-160c18.3 HLA-DPB1 ENSDARG00000053738 None Not determined 7
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-160c18.3 HLA-DPB2 ENSDARG00000093706 None Not determined 2
si:busm1-160c18.3 HLA-DQB1 ENSDARG00000093706 None Not determined 24
si:busm1-160c18.3 HLA-DPB1 ENSDARG00000093706 None Not determined 7
si:busm1-194e12.11 HLA-DQA1 ENSDARG00000055441 None Not determined 27
si:busm1-194e12.11 HLA-DPA1 ENSDARG00000055441 None Not determined 4
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-194e12.12 HLA-DPB2 ENSDARG00000055447 None Not determined 2
si:busm1-194e12.12 HLA-DQB1 ENSDARG00000055447 None Not determined 24
si:busm1-194e12.12 HLA-DPB1 ENSDARG00000055447 None Not determined 7
si:busm1-228j01.3 HLA-DQA1 ENSDARG00000086294 3 Not determined 27
si:busm1-228j01.3 HLA-DPA1 ENSDARG00000086294 3 Not determined 4
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 1 Not determined 35
si:busm1-228j01.4 HLA-DPB2 ENSDARG00000088872 1 Not determined 2
si:busm1-228j01.4 HLA-DQB1 ENSDARG00000088872 1 Not determined 24
si:busm1-228j01.4 HLA-DPB1 ENSDARG00000088872 1 Not determined 7
si:busm1-228j01.5 HLA-DQA1 ENSDARG00000079593 1 Not determined 27
si:busm1-228j01.5 HLA-DPA1 ENSDARG00000079593 1 Not determined 4
si:busm1-228j01.6 HLA-DPB2 ENSDARG00000041705 None Not determined 2
si:busm1-228j01.6 HLA-DQB1 ENSDARG00000041705 None Not determined 24
si:busm1-228j01.6 HLA-DPB1 ENSDARG00000041705 None Not determined 7
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 None Not determined 35
si:ch1073-403i13.1 HLA-DQA1 ENSDARG00000001832 None Not determined 27
si:ch1073-403i13.1 HLA-DPA1 ENSDARG00000001832 None Not determined 4
si:ch73-100n10.1 MTMR3 ENSDARG00000093364 2 Not determined 6
si:ch73-211l2.3 HLA-DQA1 ENSDARG00000075932 1 Not determined 27
si:ch73-211l2.3 HLA-DPA1 ENSDARG00000075932 1 Not determined 4
si:dkey-114d20.1 CFHR1 ENSDARG00000092786 None Not determined 2
si:dkey-114d20.1 CFHR4 ENSDARG00000092786 None Not determined 3
si:dkey-114d20.1 CFHR5 ENSDARG00000092786 None Not determined 2
si:dkey-114d20.1 CFH ENSDARG00000092786 None Not determined 12
si:dkey-114d20.1 CFHR3 ENSDARG00000092786 None Not determined 4
si:dkey-114d20.3 CFHR1 ENSDARG00000091868 None Not determined 2
si:dkey-114d20.3 CFHR4 ENSDARG00000091868 None Not determined 3
si:dkey-114d20.3 CFHR5 ENSDARG00000091868 None Not determined 2
si:dkey-114d20.3 CFH ENSDARG00000091868 None Not determined 12
si:dkey-114d20.3 CFHR3 ENSDARG00000091868 None Not determined 4
si:dkeyp-2h4.2 HLA-DQA1 ENSDARG00000031745 None Not determined 27
si:dkeyp-2h4.2 HLA-DPA1 ENSDARG00000031745 None Not determined 4
si:zfos-2070c2.1 HLA-DQA1 ENSDARG00000070206 None Not determined 27
si:zfos-2070c2.1 HLA-DPA1 ENSDARG00000070206 None Not determined 4
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
si:zfos-2070c2.3 HLA-DPB2 ENSDARG00000076307 None Not determined 2
si:zfos-2070c2.3 HLA-DQB1 ENSDARG00000076307 None Not determined 24
si:zfos-2070c2.3 HLA-DPB1 ENSDARG00000076307 None Not determined 7
si:zfos-367g9.1 HLA-DQA1 ENSDARG00000074816 1 Not determined 27
si:zfos-367g9.1 HLA-DPA1 ENSDARG00000074816 1 Not determined 4
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
wu:fd58b11 HLA-DPB2 ENSDARG00000054921 None Not determined 2
wu:fd58b11 HLA-DQB1 ENSDARG00000054921 None Not determined 24
wu:fd58b11 HLA-DPB1 ENSDARG00000054921 None Not determined 7
zgc:123107 HLA-DPA1 ENSDARG00000020286 None Not determined 4
zgc:123107 HLA-DQA1 ENSDARG00000020286 None Not determined 27
zgc:153067 HLA-DPB1 ENSDARG00000056330 1 Not determined 7
zgc:153067 HLA-DRB1 ENSDARG00000056330 1 Not determined 35
zgc:153067 HLA-DPB2 ENSDARG00000056330 1 Not determined 2
zgc:153067 HLA-DQB1 ENSDARG00000056330 1 Not determined 24
zgc:77875 MTMR3 ENSDARG00000058305 2 Not determined 6

The following reported genes could not be linked automatically to a zebrafish gene:

  • CHFR2
  • HORMAD2
  • LIF
  • OSM
* quick link - http://q.sanger.ac.uk/ptbghikd