GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A4IGH1_DANRE RASD1 ENSDARG00000026383 None Not determined 1
anks1a ANKS1A ENSDARG00000062396 3 Not determined 4
ANKS1A (2 of 2) ANKS1A ENSDARG00000078901 2 Not determined 4
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
apoa4 APOA4 ENSDARG00000040298 1 Not determined 11
apoa4 APOA1 ENSDARG00000040298 1 Not determined 13
cdkn2b CDKN2B ENSDARG00000037262 None Not determined 30
cdkn2b CDKN2A ENSDARG00000037262 None Not determined 25
cnnm2a CNNM2 ENSDARG00000061195 2 Not determined 9
cnnm2b CNNM2 ENSDARG00000078733 2 Not determined 9
col4a1 COL4A1 ENSDARG00000055009 3 Not determined 3
col4a2 COL4A2 ENSDARG00000020781 4 Not determined 2
cxcl12a CXCL12 ENSDARG00000037116 1 Not determined 4
cxcl12b CXCL12 ENSDARG00000055100 3 Not determined 4
cyp17a1 CYP17A1 ENSDARG00000033566 2 Not determined 7
cyp17a2 CYP17A1 ENSDARG00000053966 None Not determined 7
hhipl1 HHIPL1 ENSDARG00000062501 3 Not determined 1
ldlr LDLR ENSDARG00000029476 1 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
mia3 MIA3 ENSDARG00000008184 1 Not determined 3
nt5c2a NT5C2 ENSDARG00000039399 3 Not determined 9
nt5c2b NT5C2 ENSDARG00000058231 2 Not determined 9
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
pemt PEMT ENSDARG00000040450 None Not determined 1
plg LPA ENSDARG00000023111 2 Not determined 10
ppap2b PPAP2B ENSDARG00000059933 None Not determined 4
Q5SP03_DANRE MIA3 ENSDARG00000095703 None Not determined 3
rasd1 RASD1 ENSDARG00000019274 None Not determined 1
SH2B3 (1 of 2) SH2B3 ENSDARG00000069958 None Not determined 19
si:ch211-136a13.1 HHIPL1 ENSDARG00000060927 1 Not determined 1
si:dkey-159a18.1 SORT1 ENSDARG00000056145 1 Not determined 13
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-7f3.15 APOA5 ENSDARG00000094929 None Not determined 22
si:dkey-7f3.15 APOA4 ENSDARG00000094929 None Not determined 11
si:dkey-7f3.15 APOA1 ENSDARG00000094929 None Not determined 13
si:dkeyp-1e8.2 SH2B3 ENSDARG00000093095 None Not determined 19
si:rp71-1n18.3 MRAS ENSDARG00000062865 None Not determined 2
si:rp71-1n18.3 MRAS ENSDARG00000075285 None Not determined 2
smg6 SMG6 ENSDARG00000075957 1 Not determined 5
snf8 SNF8 ENSDARG00000058076 None Not determined 1
sort1a SORT1 ENSDARG00000029402 None Not determined 13
sort1b SORT1 ENSDARG00000056252 7 Not determined 13
tcf21 TCF21 ENSDARG00000036869 None Not determined 2
wdr12 WDR12 ENSDARG00000003287 None Not determined 2
zc3hc1 ZC3HC1 ENSDARG00000062651 3 Not determined 1
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:114118 RASD1 ENSDARG00000052222 None Not determined 1
zgc:152698 RASD1 ENSDARG00000058464 None Not determined 1
zgc:153390 MRPS6 ENSDARG00000039543 None Not determined 2
zgc:153845 RASD1 ENSDARG00000012772 None Not determined 1
zgc:158309 PPAP2B ENSDARG00000069940 3 Not determined 4
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:73293 ATP5G1 ENSDARG00000056008 None Not determined 1
zgc:92419 UBE2Z ENSDARG00000029215 1 Not determined 1
znf259 ZNF259 ENSDARG00000043542 1 Not determined 11

The following reported genes could not be linked automatically to a zebrafish gene:

  • ABO
  • ADAMTS7
  • APOC3
  • GIP
  • PHACTR1
  • SMCR3
  • SRR
* quick link - http://q.sanger.ac.uk/r3rcbtv7