GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
cacna1da CACNA1D ENSDARG00000024004 2 Normal 3
casq2 CASQ2 ENSDARG00000008982 None Not determined 1
cdkn1a CDKN1A ENSDARG00000076554 None Not determined 4
cdkn1c CDKN1A ENSDARG00000010878 1 Not determined 4
crim1 CRIM1 ENSDARG00000029668 4 Not determined 2
dkk1a DKK1 ENSDARG00000014103 None Not determined 2
dkk1b DKK1 ENSDARG00000045219 5 Not determined 2
faf1 FAF1 ENSDARG00000022418 1 Not determined 2
gosr2 GOSR2 ENSDARG00000053070 1 Not determined 3
HEATR5B (2 of 2) HEATR5B ENSDARG00000086915 None Not determined 1
igfbp3 IGFBP3 ENSDARG00000014859 1 Not determined 3
klf12a KLF12 ENSDARG00000015312 2 Not determined 3
klf12b KLF12 ENSDARG00000032197 None Not determined 3
klf3 KLF12 ENSDARG00000015495 1 Not determined 3
LOC100004175 CDKN1A ENSDARG00000089854 None Not determined 4
LOC100150844 PRKCD ENSDARG00000070651 3 Not determined 3
LOC100334188 TBX3 ENSDARG00000061509 None Not determined 8
LOC557518 TKT ENSDARG00000029689 2 Not determined 1
LOC571772 HEATR5B ENSDARG00000059116 3 Not determined 1
lrig1 LRIG1 ENSDARG00000075625 7 Normal 3
nfia NFIA ENSDARG00000062420 2 Not determined 6
NP_001038387.1 SCN10A ENSDARG00000059692 6 Not determined 8
NP_001038387.1 SCN5A ENSDARG00000059692 6 Not determined 9
prkca PRKCA ENSDARG00000039241 None Not determined 2
prkcd PRKCD ENSDARG00000009208 1 Not determined 3
Q5SPS0_DANRE C6orf204 ENSDARG00000093883 2 Not determined 5
rnf11 RNF11 ENSDARG00000010442 1 Not determined 1
sap30l SAP30L ENSDARG00000030213 None Not determined 2
sb:cb54 SIPA1L1 ENSDARG00000016945 1 Not determined 2
si:ch211-112m17.3 C6orf204 ENSDARG00000020777 3 Not determined 5
si:ch211-165l2.2 CDKN2C ENSDARG00000057610 None Not determined 1
si:ch211-198e13.1 SETBP1 ENSDARG00000093799 1 Not determined 2
sipa1l1 SIPA1L1 ENSDARG00000020134 3 Not determined 2
slc25a26 SLC25A26 ENSDARG00000058208 2 Not determined 1
slc35f1 SLC35F1 ENSDARG00000053003 None Not determined 6
STRN STRN ENSDARG00000060595 None Not determined 1
tbx16 TBX3 ENSDARG00000007329 None Not determined 8
tbx20 TBX20 ENSDARG00000005150 1 Not determined 1
tbx3 TBX3 ENSDARG00000002216 5 Normal 8
tbx5a TBX5 ENSDARG00000024894 None Not determined 10
tbx5b TBX5 ENSDARG00000092060 None Not determined 10
tbx6 TBX3 ENSDARG00000006939 1 Not determined 8
vti1a VTI1A ENSDARG00000045065 None Not determined 3
zgc:114095 RNF11 ENSDARG00000040635 1 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • BRD7P3
  • C1orf185
  • HAND1
  • PLN
Short-link