GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genetic variants influencing circulating lipid levels and risk of coronary artery disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
abca1a ABCA1 ENSDARG00000074635 9 Not determined 13
AFF1 AFF1 ENSDARG00000086044 1 Not determined 4
angptl3 ANGPTL3 ENSDARG00000044365 None Not determined 7
apoa1 APOA5 ENSDARG00000012076 1 Not determined 22
apoa1 APOA4 ENSDARG00000012076 1 Not determined 11
apoa1 APOA1 ENSDARG00000012076 1 Not determined 13
apoa4 APOA1 ENSDARG00000040298 1 Not determined 13
apoa4 APOA5 ENSDARG00000040298 1 Not determined 22
apoa4 APOA4 ENSDARG00000040298 1 Not determined 11
apob APOB ENSDARG00000042780 7 Not determined 17
apobl APOB ENSDARG00000022767 6 Not determined 17
apoeb APOE ENSDARG00000040295 None Not determined 42
baz1b BAZ1B ENSDARG00000061394 2 Not determined 3
bcl7ba BCL7B ENSDARG00000026709 None Not determined 3
bcl7bb BCL7B ENSDARG00000040396 None Not determined 3
celsr1a CELSR2 ENSDARG00000069185 3 Not determined 17
CELSR2 CELSR2 ENSDARG00000088231 3 Not determined 17
celsr2l CELSR2 ENSDARG00000019726 1 Not determined 17
cetp CETP ENSDARG00000030872 1 Not determined 27
dock7 DOCK7 ENSDARG00000078675 5 Not determined 5
gmpr GMPR ENSDARG00000016160 None Not determined 4
hmgcra HMGCR ENSDARG00000052734 1 Not determined 9
hmgcrb HMGCR ENSDARG00000059301 1 Not determined 9
kctd10 KCTD10 ENSDARG00000017115 None Not determined 1
ldlr LDLR ENSDARG00000029476 1 Not determined 15
LDLR (2 of 2) LDLR ENSDARG00000089730 None Not determined 15
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
lipg LIPG ENSDARG00000031044 1 Not determined 9
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC100332488 TBL2 ENSDARG00000043357 None Not determined 4
LOC100332907 BAZ1B ENSDARG00000053572 1 Not determined 3
LOC100333044 GCKR ENSDARG00000086620 None Not determined 39
LOC793111 C5orf35 ENSDARG00000074456 2 Not determined 1
LOC793137 LCAT ENSDARG00000062375 None Not determined 6
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 None Not determined 21
mmab MMAB ENSDARG00000068344 1 Not determined 4
mvk MVK ENSDARG00000004130 None Not determined 4
mylipa MYLIP ENSDARG00000008859 None Not determined 3
mylipb MYLIP ENSDARG00000055118 None Not determined 3
PCSK9 PCSK9 ENSDARG00000074185 1 Not determined 10
ppp1r3b PPP1R3B ENSDARG00000044691 None Not determined 9
si:ch1073-189o9.1 MLXIPL ENSDARG00000089107 None Not determined 13
si:ch211-212d10.4 CILP2 ENSDARG00000013687 2 Not determined 5
si:dkey-162b3.1 GALNT2 ENSDARG00000003829 4 Not determined 8
si:dkey-205h13.2 CILP2 ENSDARG00000089429 1 Not determined 5
si:dkey-242g16.2 PPP1R3B ENSDARG00000069377 None Not determined 9
si:dkey-258f14.3 LDLR ENSDARG00000075974 None Not determined 15
si:dkey-30k22.7 CELSR2 ENSDARG00000037286 3 Not determined 17
si:dkey-7f3.15 APOA5 ENSDARG00000094929 None Not determined 22
si:dkey-7f3.15 APOA4 ENSDARG00000094929 None Not determined 11
si:dkey-7f3.15 APOA1 ENSDARG00000094929 None Not determined 13
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-69c1.6 BUD13 ENSDARG00000006666 2 Not determined 8
si:dkeyp-88f5.1 APOB ENSDARG00000075016 3 Not determined 17
tbl2 TBL2 ENSDARG00000074603 None Not determined 4
trib1 TRIB1 ENSDARG00000076142 1 Not determined 12
ube3b UBE3B ENSDARG00000061960 3 Not determined 1
zgc:110064 APOE ENSDARG00000086370 None Not determined 42
zgc:112992 APOA5 ENSDARG00000086281 None Not determined 22
zgc:112992 APOA4 ENSDARG00000086281 None Not determined 11
zgc:112992 APOA1 ENSDARG00000086281 None Not determined 13
zgc:153587 GFOD2 ENSDARG00000061145 None Not determined 1
zgc:171581 ABCA1 ENSDARG00000079009 5 Not determined 13
zgc:194131 APOA5 ENSDARG00000020866 2 Not determined 22
zgc:194131 APOA4 ENSDARG00000020866 2 Not determined 11
zgc:194131 APOA1 ENSDARG00000020866 2 Not determined 13
zgc:77112 PPP1R3B ENSDARG00000015657 None Not determined 9
znf259 ZNF259 ENSDARG00000043542 1 Not determined 11

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOC1
  • APOC2
  • APOC3
  • APOC3
  • APOC3
  • APOC4
  • FADS1
  • FADS1
  • MYO1H
  • SF4
  • TTC39B
  • ZNF101
* quick link - http://q.sanger.ac.uk/693zjjk0