GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A1L2D9_DANRE CFI ENSDARG00000036900 None Not determined 4
A4QP95_DANRE C2 ENSDARG00000019772 2 Not determined 5
bfb CFB ENSDARG00000005616 3 Not determined 6
C3 (1 of 9) C3 ENSDARG00000090176 None Not determined 6
c3b C3 ENSDARG00000087359 5 Not determined 6
c3c C3 ENSDARG00000052207 2 Not determined 6
cetp CETP ENSDARG00000030872 1 Not determined 27
cfb CFB ENSDARG00000055278 3 Not determined 6
cfh CFH ENSDARG00000075761 1 Not determined 12
cfhl1 CFH ENSDARG00000056771 None Not determined 12
cfhl2 CFH ENSDARG00000056778 3 Not determined 12
cfhl3 CFH ENSDARG00000094661 None Not determined 12
cfhl4 CFH ENSDARG00000094496 None Not determined 12
htra1a HTRA1 ENSDARG00000032831 5 Normal 9
htra1b HTRA1 ENSDARG00000014907 3 Not determined 9
lipc LIPC ENSDARG00000053476 2 Not determined 24
LIPC (2 of 2) LIPC ENSDARG00000090486 None Not determined 24
LOC100331428 C3 ENSDARG00000093198 None Not determined 6
Q5RI69_DANRE CFH ENSDARG00000094134 None Not determined 12
si:ch211-140f21.1 C3 ENSDARG00000001818 3 Not determined 6
si:dkey-114d20.1 CFH ENSDARG00000092786 None Not determined 12
si:dkey-114d20.3 CFH ENSDARG00000091868 None Not determined 12
si:dkey-21e7.2 C3 ENSDARG00000093068 1 Not determined 6
si:dkey-76b14.4 C3 ENSDARG00000012694 5 Normal 6
si:dkey-76b14.5 C3 ENSDARG00000053462 3 Not determined 6
zgc:103710 C3 ENSDARG00000043719 None Not determined 6
zgc:158446 CFB ENSDARG00000090730 3 Not determined 6

The following reported genes could not be linked automatically to a zebrafish gene:

  • ARMS2
  • TIMP3
* quick link - http://q.sanger.ac.uk/mbxiaklb