GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

A genome-wide association study in 19 633 Japanese subjects identified LHX3-QSOX2 and IGF1 as adult height loci.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ADAMTSL3 ADAMTSL3 ENSDARG00000027903 6 Not determined 8
atf7a ATF7 ENSDARG00000011298 1 Not determined 2
atf7b ATF7 ENSDARG00000055481 None Not determined 2
atp13a2 ATP13A2 ENSDARG00000061890 5 Not determined 1
CDCA7L CDCA7L ENSDARG00000076659 None Not determined 1
cdh5 CDH13 ENSDARG00000075549 5 Not determined 15
cyp19a1a CYP19A1 ENSDARG00000041348 1 Not determined 6
cyp19a1b CYP19A1 ENSDARG00000009852 2 Not determined 6
dhh IHH ENSDARG00000037062 None Not determined 4
gdf5 GDF5 ENSDARG00000002760 1 Not determined 5
gdf7 GDF5 ENSDARG00000042784 None Not determined 5
glt25d2 GLT25D2 ENSDARG00000014670 1 Not determined 3
gna12 GNA12 ENSDARG00000025826 None Not determined 7
GPC5 GPC5 ENSDARG00000088858 None Not determined 9
hmga1 HMGA1 ENSDARG00000028335 1 Not determined 9
igf1 IGF1 ENSDARG00000094132 None Not determined 5
ihha IHH ENSDARG00000058733 1 Normal 4
ihhb IHH ENSDARG00000058815 1 Not determined 4
LHX3 LHX3 ENSDARG00000003803 None Not determined 1
LOC100332567 EFEMP1 ENSDARG00000059121 None Not determined 8
LOC559603 QSOX2 ENSDARG00000077174 2 Normal 2
LOC562072 LTBP1 ENSDARG00000056922 8 Not determined 4
LOC797518 GNA12 ENSDARG00000037619 None Not determined 7
ncapg NCAPG ENSDARG00000070109 1 Not determined 2
NP_001099135.1 CABLES1 ENSDARG00000062044 None Not determined 6
NTAN1 NTAN1 ENSDARG00000079495 1 Not determined 2
pdxdc1 PDXDC1 ENSDARG00000007549 None Not determined 4
plag1 PLAG1 ENSDARG00000051926 1 Not determined 5
plekha1 PLEKHA1 ENSDARG00000030064 1 Not determined 2
PLEKHA1 (2 of 2) PLEKHA1 ENSDARG00000094504 None Not determined 2
ptpn9 PTPN9 ENSDARG00000077495 2 Not determined 1
ptpn9b PTPN9 ENSDARG00000073902 4 Not determined 1
sdhb SDHB ENSDARG00000075768 1 Not determined 1
si:ch211-122a20.1 CDH13 ENSDARG00000014215 1 Not determined 15
si:ch211-13f8.2 GLT25D2 ENSDARG00000078299 3 Not determined 3
si:ch211-273k1.4 DIS3L2 ENSDARG00000033259 None Not determined 3
si:ch211-93a19.1 DGKH ENSDARG00000018716 4 Not determined 3
si:ch73-160p19.2 ZBTB38 ENSDARG00000077426 None Not determined 12
si:dkey-172j4.3 DGKH ENSDARG00000074183 3 Not determined 3
si:dkey-236e20.9 GPC5 ENSDARG00000024588 2 Not determined 9
si:dkey-250m6.8 EFEMP1 ENSDARG00000070996 None Not determined 8
sin3aa SIN3A ENSDARG00000079716 2 Not determined 2
sin3ab SIN3A ENSDARG00000059812 2 Not determined 2
zgc:153206 UQCC ENSDARG00000068176 None Not determined 6
zgc:153948 HMGA1 ENSDARG00000070951 2 Not determined 9
zgc:73293 ATP5G2 ENSDARG00000056008 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • LCORL
* quick link - http://q.sanger.ac.uk/qz1xvqlm