GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
A5WWE7_DANRE ALDH2 ENSDARG00000037094 None Not determined 12
adh8a ADH1B ENSDARG00000091211 2 Not determined 5
adh8a ADH6 ENSDARG00000091211 2 Not determined 2
adh8b ADH1B ENSDARG00000024278 1 Not determined 5
adh8b ADH6 ENSDARG00000024278 1 Not determined 2
ALDH2 (3 of 4) ALDH2 ENSDARG00000090766 None Not determined 12
aldh2a ALDH2 ENSDARG00000089924 1 Not determined 12
aldh2b ALDH2 ENSDARG00000028087 None Not determined 12
brap BRAP ENSDARG00000008560 3 Not determined 4
zgc:63568 ADH6 ENSDARG00000087262 2 Not determined 2
zgc:63568 ADH1B ENSDARG00000087262 2 Not determined 5
zgc:77938 ADH6 ENSDARG00000088366 2 Not determined 2
zgc:77938 ADH1B ENSDARG00000088366 2 Not determined 5
* quick link - http://q.sanger.ac.uk/kvinrymy