GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
arid2 ARID2 ENSDARG00000007413 2 Not determined 1
ARSB ARSB ENSDARG00000093887 None Not determined 2
cand1 CAND1 ENSDARG00000017841 1 Not determined 1
efna5a EFNA5 ENSDARG00000089790 None Not determined 2
efna5b EFNA5 ENSDARG00000057223 1 Not determined 2
frmd6 FRMD6 ENSDARG00000002332 2 Not determined 4
ikzf1 IKZF1 ENSDARG00000013539 3 Not determined 10
lhfpl2 LHFPL2 ENSDARG00000039926 None Not determined 1
magi2 MAGI2 ENSDARG00000021590 4 Not determined 4
MAGI2 (2 of 3) MAGI2 ENSDARG00000089764 None Not determined 4
MAGI2 (1 of 3) MAGI2 ENSDARG00000073769 1 Not determined 4
NP_001017562.1 LHFPL2 ENSDARG00000071509 None Not determined 1
rpn2 RPN2 ENSDARG00000009724 None Not determined 1
si:ch211-157c18.2 MAGI2 ENSDARG00000025108 2 Not determined 4
si:ch211-66g24.1 MAGI2 ENSDARG00000077633 1 Not determined 4
si:dkey-267i17.5 PRUNE2 ENSDARG00000059423 None Not determined 1
zgc:77456 LHFPL2 ENSDARG00000009653 None Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • C20orf132
  • FDPSP
  • MAL2
  • RP11-232A1.1
  • S100A5
  • SCAMP1
  • SFRS2IP
  • ZBP1
* quick link - http://q.sanger.ac.uk/6usn58rz