GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
asap1 ASAP1 ENSDARG00000002607 7 Normal 1
asap1 ASAP1 ENSDARG00000039729 2 Not determined 1
CYP27B1 CYP27B1 ENSDARG00000045015 None Not determined 2
evi5 EVI5 ENSDARG00000070839 None Not determined 3
mhc2dab HLA-DRB1 ENSDARG00000079105 None Not determined 35
NP_001091732.1 HLA-DRB1 ENSDARG00000071168 1 Not determined 35
rpl5a RPL5 ENSDARG00000020197 None Not determined 3
rpl5b RPL5 ENSDARG00000015862 None Not determined 3
si:busm1-104n07.3 HLA-DRB1 ENSDARG00000074510 1 Normal 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000053738 None Not determined 35
si:busm1-160c18.3 HLA-DRB1 ENSDARG00000093706 None Not determined 35
si:busm1-194e12.12 HLA-DRB1 ENSDARG00000055447 None Not determined 35
si:busm1-228j01.4 HLA-DRB1 ENSDARG00000088872 1 Not determined 35
si:busm1-228j01.6 HLA-DRB1 ENSDARG00000041705 None Not determined 35
si:ch211-160i2.3 ASAP1 ENSDARG00000029463 2 Not determined 1
si:zfos-2070c2.3 HLA-DRB1 ENSDARG00000076307 None Not determined 35
wu:fd58b11 HLA-DRB1 ENSDARG00000054921 None Not determined 35
zgc:103636 METTL1 ENSDARG00000076518 None Not determined 1
zgc:153067 HLA-DRB1 ENSDARG00000056330 1 Not determined 35

The following reported genes could not be linked automatically to a zebrafish gene:

  • CD40
  • CD58
  • DDEF1
  • IL2RA
* quick link - http://q.sanger.ac.uk/6xl357fl