GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Meta-analysis of genome-wide scans for human adult stature identifies novel Loci and associations with measures of skeletal frame size.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ADAMTSL3 ADAMTSL3 ENSDARG00000027903 6 Not determined 8
gna12 GNA12 ENSDARG00000025826 None Not determined 7
gpr126 GPR126 ENSDARG00000054137 3 1 phenotype 9
hhip HHIP ENSDARG00000060397 1 Not determined 13
hmga1 HMGA1 ENSDARG00000028335 1 Not determined 9
hmga2 HMGA2 ENSDARG00000069912 None Not determined 18
jazf1a JAZF1 ENSDARG00000036243 1 Not determined 8
jazf1b JAZF1 ENSDARG00000056793 None Not determined 8
LOC100333070 HIST1H1D ENSDARG00000088889 None Not determined 2
LOC100333275 HIST1H1D ENSDARG00000075508 None Not determined 2
LOC100334833 HMGA2 ENSDARG00000091038 None Not determined 18
LOC556339 PRKG2 ENSDARG00000062839 2 Not determined 4
LOC560910 HIST1H1D ENSDARG00000032637 None Not determined 2
LOC569515 CDK6 ENSDARG00000030163 1 Not determined 8
LOC573073 HIST1H1D ENSDARG00000051718 None Not determined 2
LOC797518 GNA12 ENSDARG00000037619 None Not determined 7
npr3 NPR3 ENSDARG00000035253 2 Not determined 7
plag1 PLAG1 ENSDARG00000051926 1 Not determined 5
prkg2 PRKG2 ENSDARG00000054741 1 Not determined 4
si:ch211-103n10.5 HIST1H1D ENSDARG00000077504 None Not determined 2
si:ch211-234f14.1 CDK6 ENSDARG00000070228 None Not determined 8
si:ch73-160h15.3 DLEU7 ENSDARG00000094160 None Not determined 6
si:ch73-160p19.2 ZBTB38 ENSDARG00000077426 None Not determined 12
si:dkey-121j17.5 PRKG2 ENSDARG00000014232 5 Not determined 4
tmed10 TMED10 ENSDARG00000041391 None Not determined 1
zgc:101577 C6orf106 ENSDARG00000078075 None Not determined 4
zgc:110216 HIST1H1D ENSDARG00000077456 None Not determined 2
zgc:110380 HIST1H1D ENSDARG00000035519 None Not determined 2
zgc:110425 HIST1H1D ENSDARG00000058479 None Not determined 2
zgc:153206 UQCC ENSDARG00000068176 None Not determined 6
zgc:153948 HMGA1 ENSDARG00000070951 2 Not determined 9
zgc:163061 HIST1H1D ENSDARG00000075538 None Not determined 2
zgc:163061 HIST1H1D ENSDARG00000076766 None Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • CATSPER4
  • HLA-B
  • LCORL
  • WDR40A
* quick link - http://q.sanger.ac.uk/bsvqze7s