GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
acp5a ACP5 ENSDARG00000019763 3 Not determined 1
acp5b ACP5 ENSDARG00000008921 2 Not determined 1
c1galt1a C1GALT1 ENSDARG00000055585 None Not determined 2
c1galt1b C1GALT1 ENSDARG00000055561 None Not determined 2
cbln2a CBLN2 ENSDARG00000074601 None Not determined 3
cbln2b CBLN2 ENSDARG00000077151 1 Not determined 3
chrnd CHRND ENSDARG00000019342 2 Not determined 1
CSMD1 CSMD1 ENSDARG00000058353 1 Not determined 12
eng1a EN1 ENSDARG00000014321 None Not determined 1
eng1b EN1 ENSDARG00000015073 2 Normal 1
foxo3a FOXO3 ENSDARG00000023058 3 Not determined 2
foxo3b FOXO3 ENSDARG00000042904 None Not determined 2
GPC5 GPC5 ENSDARG00000088858 None Not determined 9
igf2r IGF2R ENSDARG00000006094 4 Not determined 1
jarid2a JARID2 ENSDARG00000060925 3 Not determined 3
jarid2b JARID2 ENSDARG00000062268 3 Not determined 3
kcnb2 KCNB2 ENSDARG00000038862 1 Not determined 4
kcnip1a KCNIP1 ENSDARG00000022109 None Not determined 1
kcnip1b KCNIP1 ENSDARG00000034808 3 Not determined 1
LOC100330316 BICD1 ENSDARG00000074357 2 Not determined 4
LOC100332173 WDR7 ENSDARG00000088043 None Not determined 2
LOC564281 C1GALT1 ENSDARG00000074025 None Not determined 2
LOC572502 WDR7 ENSDARG00000059329 1 Not determined 2
LOC797493 C20orf46 ENSDARG00000078868 None Not determined 1
met MET ENSDARG00000070903 4 Not determined 1
mxi1 MXI1 ENSDARG00000040884 None Not determined 1
NP_001030338.2 SVIL ENSDARG00000055075 7 Not determined 1
nubpl NUBPL ENSDARG00000054821 1 Not determined 2
PDZRN4 (1 of 2) PDZRN4 ENSDARG00000086878 1 Not determined 2
rab32b RAB38 ENSDARG00000041165 None Not determined 1
rab38 RAB38 ENSDARG00000028776 None Not determined 1
RELN (3 of 4) RELN ENSDARG00000038188 1 Not determined 4
RELN (2 of 4) RELN ENSDARG00000086526 1 Not determined 4
RELN (1 of 4) RELN ENSDARG00000074198 None Not determined 4
relnl RELN ENSDARG00000077935 2 Not determined 4
sgcd SGCD ENSDARG00000009789 2 Not determined 3
sh3gl2 SH3GL2 ENSDARG00000023600 2 Not determined 5
SH3GL2 (1 of 2) SH3GL2 ENSDARG00000039901 None Not determined 5
si:ch211-136i24.1 BICD1 ENSDARG00000079496 4 Normal 4
si:ch211-145b13.5 KCNIP1 ENSDARG00000037256 1 Not determined 1
si:ch211-87h14.4 CPAMD8 ENSDARG00000092844 None Not determined 2
si:ch73-173m3.3 RAB38 ENSDARG00000074719 1 Not determined 1
si:dkey-149i17.7 ZIC1 ENSDARG00000094684 None Not determined 1
si:dkey-162f21.5 RFK ENSDARG00000060522 None Not determined 1
si:dkey-171o17.5 C1orf125 ENSDARG00000062355 3 Not determined 1
si:dkey-192j17.1 KCNB2 ENSDARG00000088842 1 Not determined 4
si:dkey-202e17.1 C1GALT1 ENSDARG00000062278 None Not determined 2
si:dkey-236e20.9 GPC5 ENSDARG00000024588 2 Not determined 9
si:dkey-240a12.3 PDZRN4 ENSDARG00000045687 2 Not determined 2
si:dkey-42d18.3 SVIL ENSDARG00000014651 13 Not determined 1
si:dkey-76a19.3 RAB38 ENSDARG00000069159 None Not determined 1
si:dkey-94n12.1 CPAMD8 ENSDARG00000056530 None Not determined 2
si:dkeyp-94b4.1 SVIL ENSDARG00000038138 3 Not determined 1
slc25a36a SLC25A36 ENSDARG00000038731 1 Not determined 2
slc25a36b SLC25A36 ENSDARG00000015915 None Not determined 2
zgc:162171 RAB38 ENSDARG00000036499 None Not determined 1
zgc:162200 BICD1 ENSDARG00000079934 1 Not determined 4
zic1 ZIC1 ENSDARG00000015567 3 Not determined 1
zic6 ZIC1 ENSDARG00000071496 1 Not determined 1

The following reported genes could not be linked automatically to a zebrafish gene:

  • C16orf47
  • CENPC1
  • DDEF2
  • FLJ16641
  • FLJ34870
  • LOC132321
  • MGC13125
  • MGC45800
  • NLRP11
* quick link - http://q.sanger.ac.uk/vgad33e2