GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analysis identifies 20 loci that influence adult height.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ACAN (2 of 2) ACAN ENSDARG00000045799 1 Not determined 3
acana ACAN ENSDARG00000035891 1 Not determined 3
ADAMTSL3 ADAMTSL3 ENSDARG00000027903 6 Not determined 8
cep63 CEP63 ENSDARG00000056862 1 Not determined 1
dhh IHH ENSDARG00000037062 None Not determined 4
gdf5 GDF5 ENSDARG00000002760 1 Not determined 5
gdf7 GDF5 ENSDARG00000042784 None Not determined 5
hhip HHIP ENSDARG00000060397 1 Not determined 13
hmga2 HMGA2 ENSDARG00000069912 None Not determined 18
ihha IHH ENSDARG00000058733 1 Normal 4
ihhb IHH ENSDARG00000058815 1 Not determined 4
LOC100332567 EFEMP1 ENSDARG00000059121 None Not determined 8
LOC100334833 HMGA2 ENSDARG00000091038 None Not determined 18
LOC569515 CDK6 ENSDARG00000030163 1 Not determined 8
ncana ACAN ENSDARG00000067820 1 Not determined 3
ncanb ACAN ENSDARG00000005783 1 Not determined 3
ptch1 PTCH1 ENSDARG00000016404 6 Normal 3
si:ch211-119o8.6 ZNF678 ENSDARG00000026972 1 Not determined 1
si:ch211-167h3.1 DYM ENSDARG00000042555 5 Not determined 4
si:ch211-234f14.1 CDK6 ENSDARG00000070228 None Not determined 8
si:ch73-160h15.3 DLEU7 ENSDARG00000094160 None Not determined 6
si:ch73-160p19.2 ZBTB38 ENSDARG00000077426 None Not determined 12
si:dkey-208b23.5 SPAG17 ENSDARG00000058280 7 Not determined 3
si:dkey-250m6.8 EFEMP1 ENSDARG00000070996 None Not determined 8
si:dkey-269g4.3 ANAPC13 ENSDARG00000078435 None Not determined 1
socs2 SOCS2 ENSDARG00000045557 1 Not determined 4
zgc:101577 C6orf106 ENSDARG00000078075 None Not determined 4
zgc:162582 SCMH1 ENSDARG00000069932 3 Not determined 2

The following reported genes could not be linked automatically to a zebrafish gene:

  • LCORL
  • LOC387103
* quick link - http://q.sanger.ac.uk/5extehqw