GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Many sequence variants affecting diversity of adult human height.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
ADAMTS17 ADAMTS17 ENSDARG00000075555 None Not determined 2
ADAMTSL3 ADAMTSL3 ENSDARG00000027903 6 Not determined 8
adcy3 ADCY3 ENSDARG00000017437 2 Not determined 6
ADCY3 (1 of 2) ADCY3 ENSDARG00000077145 None Not determined 6
akap9 CEP250 ENSDARG00000079610 3 Not determined 2
anks1a ANKS1A ENSDARG00000062396 3 Not determined 4
ANKS1A (2 of 2) ANKS1A ENSDARG00000078901 2 Not determined 4
atad5a ATAD5 ENSDARG00000070568 4 Not determined 1
atad5b ATAD5 ENSDARG00000005974 4 Not determined 1
ATXN3L ATXN3 ENSDARG00000009264 None Not determined 3
bcas3 BCAS3 ENSDARG00000054893 2 Normal 8
bcas3 BCAS3 ENSDARG00000090764 None Not determined 8
bcr BCR ENSDARG00000079286 2 Not determined 2
bmp2a BMP2 ENSDARG00000013409 None Not determined 7
bmp2b BMP2 ENSDARG00000041430 1 Not determined 7
bmp3 BMP3 ENSDARG00000060526 None Not determined 3
bmp6 BMP6 ENSDARG00000015686 None Not determined 4
C18orf45 (2 of 2) C18orf45 ENSDARG00000090841 None Not determined 1
C18orf45 (1 of 2) C18orf45 ENSDARG00000090685 None Not determined 1
cap2 CAP2 ENSDARG00000045948 None Not determined 1
cct2 CCT2 ENSDARG00000041754 None Not determined 1
CCT2 (1 of 2) CCT2 ENSDARG00000087206 None Not determined 1
cd164 CD164 ENSDARG00000013628 None Not determined 3
chchd7 CHCHD7 ENSDARG00000068156 None Not determined 2
coil COIL ENSDARG00000040070 None Not determined 1
col27a1a COL27A1 ENSDARG00000034373 None Not determined 2
col7a1l COL27A1 ENSDARG00000069692 2 Not determined 2
cpsf2 CPSF2 ENSDARG00000028971 None Not determined 3
cpsf6 CPSF6 ENSDARG00000018618 1 Not determined 1
cradd CRADD ENSDARG00000028192 None Not determined 2
CRISPLD2 CRISPLD2 ENSDARG00000088595 1 Not determined 1
crlf3 CRLF3 ENSDARG00000070261 2 Not determined 1
cryba2a CRYBA2 ENSDARG00000030349 1 Not determined 1
cryba2b CRYBA2 ENSDARG00000041925 1 Not determined 1
ddx46 DDX46 ENSDARG00000094863 1 Not determined 1
DEF6 (2 of 2) DEF6 ENSDARG00000044524 None Not determined 1
dhh IHH ENSDARG00000037062 None Not determined 4
dnmt6 DNMT3A ENSDARG00000015566 1 Not determined 3
dnmt8 DNMT3A ENSDARG00000005394 3 Normal 3
dtnb DTNB ENSDARG00000013020 2 Not determined 3
dtng DTNB ENSDARG00000077694 None Not determined 3
eif6 EIF6 ENSDARG00000020232 2 Not determined 1
ETV6 ETV6 ENSDARG00000069193 1 Not determined 2
fbln5 FBLN5 ENSDARG00000039273 1 Not determined 1
fev FEV ENSDARG00000009242 1 Not determined 2
frs2 FRS2 ENSDARG00000037353 None Not determined 3
gatad1 GATAD1 ENSDARG00000027612 None Not determined 1
gdf5 GDF5 ENSDARG00000002760 1 Not determined 5
gdf7 GDF5 ENSDARG00000042784 None Not determined 5
glt25d2 GLT25D2 ENSDARG00000014670 1 Not determined 3
gna12 GNA12 ENSDARG00000025826 None Not determined 7
golim4a GOLIM4 ENSDARG00000076498 None Not determined 2
golim4b GOLIM4 ENSDARG00000014545 1 Not determined 2
gpr126 GPR126 ENSDARG00000054137 3 1 phenotype 9
HACE1 HACE1 ENSDARG00000062280 4 Not determined 6
hhip HHIP ENSDARG00000060397 1 Not determined 13
hmga1 HMGA1 ENSDARG00000028335 1 Not determined 9
hmga2 HMGA2 ENSDARG00000069912 None Not determined 18
id:ibd5037 SV2A ENSDARG00000063456 None Not determined 1
ihha IHH ENSDARG00000058733 1 Normal 4
ihhb IHH ENSDARG00000058815 1 Not determined 4
KIF13A KIF13A ENSDARG00000069594 2 Not determined 2
LIN28B LIN28B ENSDARG00000052511 None Not determined 11
LOC100332429 PRAM1 ENSDARG00000088017 1 Not determined 1
LOC100332507 CEP250 ENSDARG00000086540 1 Not determined 2
LOC100332567 EFEMP1 ENSDARG00000059121 None Not determined 8
LOC100332569 ZBTB24 ENSDARG00000075533 None Not determined 2
LOC100333103 NOG ENSDARG00000053528 None Not determined 3
LOC100334833 HMGA2 ENSDARG00000091038 None Not determined 18
LOC556339 PRKG2 ENSDARG00000062839 2 Not determined 4
LOC568033 SV2A ENSDARG00000059945 4 Not determined 1
LOC568235 MRPL42 ENSDARG00000079391 None Not determined 1
LOC569515 CDK6 ENSDARG00000030163 1 Not determined 8
LOC792822 SPIN1 ENSDARG00000058949 1 Not determined 2
LOC797518 GNA12 ENSDARG00000037619 None Not determined 7
LOC797914 SMPD2 ENSDARG00000052701 2 Not determined 1
lrrc10 LRRC10 ENSDARG00000045612 1 Not determined 1
lyn LYN ENSDARG00000031715 2 Not determined 1
map3k3 MAP3K3 ENSDARG00000060348 1 Not determined 3
mmp24 MMP24 ENSDARG00000018896 None Not determined 2
mos MOS ENSDARG00000069744 1 Not determined 1
mt2 MT1F ENSDARG00000041623 1 Not determined 2
MTMR11 MTMR11 ENSDARG00000069755 1 Not determined 1
ncapg NCAPG ENSDARG00000070109 1 Not determined 2
nog1 NOG ENSDARG00000058819 None Not determined 3
nog3 NOG ENSDARG00000079003 None Not determined 3
NP_001099135.1 CABLES1 ENSDARG00000062044 None Not determined 6
NP_001103410.1 NPPC ENSDARG00000090921 None Not determined 3
NP_001165699.1 DGKE ENSDARG00000059735 1 Not determined 1
NP_956003.1 DTNB ENSDARG00000037388 None Not determined 3
pde6d PDE6D ENSDARG00000074892 1 Not determined 1
penk PENK ENSDARG00000036045 2 Not determined 1
penkl PENK ENSDARG00000004869 1 Not determined 1
pex1 PEX1 ENSDARG00000076647 None Not determined 1
pitx1 PITX1 ENSDARG00000042785 None Not determined 4
plag1 PLAG1 ENSDARG00000051926 1 Not determined 5
pomca POMC ENSDARG00000043135 None Not determined 4
pomcb POMC ENSDARG00000069307 1 Not determined 4
popdc1 BVES ENSDARG00000058548 None Not determined 2
popdc3 POPDC3 ENSDARG00000058551 None Not determined 3
prkg2 PRKG2 ENSDARG00000054741 1 Not determined 4
ptmaa PTMA ENSDARG00000021113 None Not determined 1
ptmab PTMA ENSDARG00000079193 None Not determined 1
rasgef1ba RASGEF1B ENSDARG00000033614 2 Not determined 2
rasgef1bb RASGEF1B ENSDARG00000044251 4 Not determined 2
RNF135 RNF135 ENSDARG00000091057 None Not determined 1
rps20 RPS20 ENSDARG00000036044 None Not determined 1
rtdr1 RTDR1 ENSDARG00000017983 1 1 phenotype, 1 normal 2
runx2a RUNX2 ENSDARG00000040261 2 Not determined 2
runx2b RUNX2 ENSDARG00000059233 2 Not determined 2
SCUBE3 SCUBE3 ENSDARG00000011490 2 Not determined 1
serpini1 SERPINI1 ENSDARG00000034168 None Not determined 1
sf3b4 SF3B4 ENSDARG00000018574 None Not determined 2
sh3gl3 SH3GL3 ENSDARG00000007302 None Not determined 3
si:ch211-10e2.3 TRIM25 ENSDARG00000068240 None Not determined 1
si:ch211-126j24.3 NPPC ENSDARG00000068126 None Not determined 3
si:ch211-13f8.2 GLT25D2 ENSDARG00000078299 3 Not determined 3
si:ch211-153f2.5 NUP153 ENSDARG00000020323 6 Normal 2
si:ch211-1n9.6 TRIM25 ENSDARG00000039468 1 Not determined 1
si:ch211-220f16.2 CEP250 ENSDARG00000007976 2 Not determined 2
si:ch211-233f10.5 COL27A1 ENSDARG00000028236 2 Not determined 2
si:ch211-234f14.1 CDK6 ENSDARG00000070228 None Not determined 8
si:ch211-265g22.4 ETV6 ENSDARG00000076512 None Not determined 2
si:ch211-273k1.4 DIS3L2 ENSDARG00000033259 None Not determined 3
si:ch211-45m15.2 L3MBTL3 ENSDARG00000025983 1 Not determined 2
si:ch73-160h15.3 DLEU7 ENSDARG00000094160 None Not determined 6
si:ch73-160p19.2 ZBTB38 ENSDARG00000077426 None Not determined 12
si:ch73-386h18.1 ZFHX4 ENSDARG00000073944 3 Not determined 1
si:ch73-38p6.4 TGS1 ENSDARG00000067916 2 Not determined 1
si:dkey-108f8.2 L3MBTL3 ENSDARG00000074346 None Not determined 2
si:dkey-121j17.5 PRKG2 ENSDARG00000014232 5 Not determined 4
si:dkey-19f21.3 DNM3 ENSDARG00000032238 2 Not determined 6
si:dkey-21p1.3 COL27A1 ENSDARG00000002295 7 Normal 2
si:dkey-230p4.1 CEP250 ENSDARG00000020834 5 Not determined 2
si:dkey-240a9.5 MYO1F ENSDARG00000078734 5 Not determined 1
si:dkey-250m6.8 EFEMP1 ENSDARG00000070996 None Not determined 8
si:dkey-29p10.4 TRIM25 ENSDARG00000017173 5 Not determined 1
si:dkey-45m5.4 ADAMTS10 ENSDARG00000075188 3 Not determined 2
si:dkey-48h7.2 PDE3A ENSDARG00000004227 1 Not determined 7
si:dkey-91m11.5 BCR ENSDARG00000042329 2 Not determined 2
si:dkey-97m3.4 FRS2 ENSDARG00000045873 None Not determined 3
si:dkeyp-15g12.1 DEF6 ENSDARG00000034717 1 Not determined 1
si:dkeyp-72h1.1 LBH ENSDARG00000095347 None Not determined 3
si:rp71-68g1.1 SLC23A3 ENSDARG00000088891 1 Not determined 1
slco1c1 SLCO1C1 ENSDARG00000016749 3 Not determined 3
slco1d1 SLCO1B3 ENSDARG00000060181 None Not determined 3
slco1f1 SLCO1C1 ENSDARG00000037605 1 Not determined 3
slco1f2 SLCO1C1 ENSDARG00000078354 None Not determined 3
slco1f3 SLCO1C1 ENSDARG00000076531 2 Not determined 3
slco1f4 SLCO1C1 ENSDARG00000045469 4 Not determined 3
smpd2 SMPD2 ENSDARG00000040523 2 Not determined 1
socs2 SOCS2 ENSDARG00000045557 1 Not determined 4
supt3h SUPT3H ENSDARG00000002776 3 Not determined 7
tbx16 TBX2 ENSDARG00000007329 None Not determined 5
tbx2a TBX2 ENSDARG00000018025 None Not determined 5
tbx2b TBX2 ENSDARG00000006120 1 Not determined 5
tbx4 TBX4 ENSDARG00000030058 None Not determined 2
tbx6 TBX2 ENSDARG00000006939 None Not determined 5
trim25 TRIM25 ENSDARG00000015865 None Not determined 1
trip11 TRIP11 ENSDARG00000078381 2 Not determined 3
ube2na UBE2N ENSDARG00000008748 1 Not determined 1
ube2nb UBE2N ENSDARG00000045877 None Not determined 1
USP10 USP10 ENSDARG00000076116 1 Not determined 1
yeats4 YEATS4 ENSDARG00000045874 None Not determined 2
zbtb24 ZBTB24 ENSDARG00000058863 None Not determined 2
zdhhc7 ZDHHC7 ENSDARG00000019484 1 Not determined 1
zfhx4 ZFHX4 ENSDARG00000075542 2 Not determined 1
zgc:110463 PPIL6 ENSDARG00000042157 None Not determined 1
zgc:113143 RBBP8 ENSDARG00000043480 None Not determined 3
zgc:153206 UQCC ENSDARG00000068176 None Not determined 6
zgc:153635 ZNF76 ENSDARG00000013279 1 Not determined 1
zgc:153948 HMGA1 ENSDARG00000070951 2 Not determined 9
zgc:158742 SH3GL3 ENSDARG00000013360 None Not determined 3
zgc:165608 TXNDC15 ENSDARG00000043249 None Not determined 1
zgc:171516 MAP3K3 ENSDARG00000074219 1 Not determined 3
zgc:63721 DEF6 ENSDARG00000012247 1 Not determined 1
zgc:66337 LBH ENSDARG00000087377 None Not determined 3
zgc:77424 CAMLG ENSDARG00000045207 None Not determined 1
zgc:77880 ZDHHC7 ENSDARG00000030563 2 Not determined 1
zgc:92594 TRIM25 ENSDARG00000089517 None Not determined 1
ZNF462 ZNF462 ENSDARG00000063381 7 Not determined 3

The following reported genes could not be linked automatically to a zebrafish gene:

  • Butyrophilin genes
  • C1orf19
  • C6orf173
  • CATSPER3
  • CCRK
  • CENTA2
  • COPS7B
  • ERVWE1
  • GNAZ
  • Histone class 1
  • Histone class 2A
  • HLA class III
  • IGLL1
  • ITM2A
  • LCORL
  • LYK5
  • LYZ
  • MNICAL1
  • NACA2
  • OR2Z1
  • PCBD2
  • PNPT1
  • PXMP3
  • RBJ
  • RDHE2
  • RISK
  • SAMD3
  • TCP11
  • TUBA1
  • WDR68
* quick link - http://q.sanger.ac.uk/0onrg132