GWAS

(GWAS data used on the Zebrafish Mutation Project Web site comes from http://www.genome.gov/gwastudies/.)

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels.

The human homologues of the following genes have been identified in this study:

Gene name Reported Gene Ensembl ID Alleles found Associated phenotype Study Count
apob APOB ENSDARG00000042780 7 Not determined 17
apobl APOB ENSDARG00000022767 6 Not determined 17
cdkal1 CDKAL1 ENSDARG00000022122 None Not determined 23
cdkn2b CDKN2B ENSDARG00000037262 None Not determined 30
cdkn2b CDKN2A ENSDARG00000037262 None Not determined 25
cetp CETP ENSDARG00000030872 1 Not determined 27
igf2bp2a IGF2BP2 ENSDARG00000003421 1 Not determined 12
igf2bp2b IGF2BP2 ENSDARG00000061661 2 Not determined 12
kcnj11 KCNJ11 ENSDARG00000051880 None Not determined 5
kcnj11l KCNJ11 ENSDARG00000031438 None Not determined 5
LOC100002134 SLC30A8 ENSDARG00000054584 2 Not determined 16
LOC100331214 LPL ENSDARG00000034667 None Not determined 21
LOC560642 SLC30A8 ENSDARG00000057629 None Not determined 16
lpl LPL ENSDARG00000087697 1 Not determined 21
LPL (1 of 2) LPL ENSDARG00000091659 None Not determined 21
pparg PPARG ENSDARG00000031848 2 2 normal 8
si:dkeyp-106c3.3 APOB ENSDARG00000093159 None Not determined 17
si:dkeyp-88f5.1 APOB ENSDARG00000075016 3 Not determined 17
tcf7l2 TCF7L2 ENSDARG00000004415 4 Not determined 23

The following reported genes could not be linked automatically to a zebrafish gene:

  • APOE cluster
  • HHEX
* quick link - http://q.sanger.ac.uk/np1wchqx