Search Zebrafish Mutation Project
e.g. ENSDARG00000093395 or slc2a11b or ENSG00000135862 or LAMC1 or sa457
You can look for mutant lines by browsing a complete list or by searching for a particular gene
BTNL2
- Ensembl ID:
- ENSDARG00000093039
- Description:
- butyrophilin-like 2 (MHC class II associated) [Source:HGNC Symbol;Acc:1142]
- Human Orthologues:
- BTN1A1, BTN2A1, BTN2A2, BTN3A1, BTN3A2, BTN3A3, BTNL2, RP5-915N17.9
- Human Descriptions:
- butyrophilin, subfamily 1, member A1 [Source:HGNC Symbol;Acc:1135]
- butyrophilin, subfamily 2, member A1 [Source:HGNC Symbol;Acc:1136]
- butyrophilin, subfamily 2, member A2 [Source:HGNC Symbol;Acc:1137]
- butyrophilin, subfamily 3, member A1 [Source:HGNC Symbol;Acc:1138]
- butyrophilin, subfamily 3, member A2 [Source:HGNC Symbol;Acc:1139]
- butyrophilin, subfamily 3, member A3 [Source:HGNC Symbol;Acc:1140]
- butyrophilin-like 2 (MHC class II associated) [Source:HGNC Symbol;Acc:1142]
- Uncharacterized protein [Source:UniProtKB/TrEMBL;Acc:A8MVZ5]
- Mouse Orthologues:
- Btn1a1, Btn2a2, Btn3a3, Btnl2, Btnl3, Btnl5, Btnl6, Btnl7, Butr1, Skint1, Skint2, Skint3, Skint4, Skint5, Skint6, Skint7, Skint8
- Mouse Descriptions:
- butyrophilin related 1 Gene [Source:MGI Symbol;Acc:MGI:2182073]
- butyrophilin, subfamily 1, member A1 Gene [Source:MGI Symbol;Acc:MGI:103118]
- butyrophilin, subfamily 2, member A2 Gene [Source:MGI Symbol;Acc:MGI:3606486]
- butyrophilin, subfamily 3, member A3 Gene [Source:MGI Symbol;Acc:MGI:1932036]
- butyrophilin-like 2 Gene [Source:MGI Symbol;Acc:MGI:1859549]
- butyrophilin-like 3 Gene [Source:MGI Symbol;Acc:MGI:1932027]
- butyrophilin-like 5 Gene [Source:MGI Symbol;Acc:MGI:1932037]
- butyrophilin-like 6 Gene [Source:MGI Symbol;Acc:MGI:1932038]
- butyrophilin-like 7 Gene [Source:MGI Symbol;Acc:MGI:2388054]
- selection and upkeep of intraepithelial T cells 1 Gene [Source:MGI Symbol;Acc:MGI:3649627]
- selection and upkeep of intraepithelial T cells 2 Gene [Source:MGI Symbol;Acc:MGI:3649629]
- selection and upkeep of intraepithelial T cells 3 Gene [Source:MGI Symbol;Acc:MGI:3045331]
- selection and upkeep of intraepithelial T cells 4 Gene [Source:MGI Symbol;Acc:MGI:2444425]
- selection and upkeep of intraepithelial T cells 5 Gene [Source:MGI Symbol;Acc:MGI:3650151]
- selection and upkeep of intraepithelial T cells 6 Gene [Source:MGI Symbol;Acc:MGI:3649262]
- selection and upkeep of intraepithelial T cells 7 Gene [Source:MGI Symbol;Acc:MGI:3041190]
- selection and upkeep of intraepithelial T cells 8 Gene [Source:MGI Symbol;Acc:MGI:3651523]
Alleles
There is 1 allele of this gene:
| Allele name | Consequence | Status | Availability Estimate |
|---|---|---|---|
| sa16505 | Nonsense | Available for shipment | Available now |
Mutation Details
- Allele Name:
- sa16505
- Current Status:
-
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs. - Availability:
-
Order Allele From ZIRC
Order Allele From EZRC - Mutation:
- T > A
- Consequence:
- Nonsense
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000141885 | Nonsense | 314 | 430 | 5 | 6 |
- Genomic Location (Zv9):
- Chromosome 7 (position 844000)
- KASP Assay ID:
- None (used for ordering genotyping assays from LGC Genomics)
- KASP Sequence:
- TGGAGATGTGTCTCTGCAGCTGGAGAMGATCAYCATTCAGGATGAAGCTW[T/A]ATTTCACTGCTAYGTCAGTGGAGAYAATGGATATGACAGTGMASAGCTGG
- Associated Phenotype:
- Not determined
GWAS
This gene's human homologue has been identified in the following GWAS studies:
- Anti-cyclic Citrullinated Peptide Antibody: Genome-wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis. (View Study)
- Asthma: Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA. (View Study)
- Asthma: Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population. (View Study)
- Coronary heart disease: Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. (View Study)
- Hepatitis C induced liver cirrhosis: A genome-wide association study of HCV-induced liver cirrhosis in the Japanese population identifies novel susceptibility loci at the MHC region. (View Study)
- HIV-1 control: Common genetic variation and the control of HIV-1 in humans. (View Study)
- Iron status biomarkers: Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels. (View Study)
- Knee osteoarthritis: New sequence variants in HLA class II/III region associated with susceptibility to knee osteoarthritis identified by genome-wide association study. (View Study)
- Lung adenocarcinoma: A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population. (View Study)
- Multiple sclerosis (OCB status): Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. (View Study)
- Primary biliary cirrhosis: Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. (View Study)
- Sarcoidosis: Genome-wide association analysis reveals 12q13.3-q14.1 as new risk locus for sarcoidosis. (View Study)
- Schizophrenia: Common variants on chromosome 6p22.1 are associated with schizophrenia. (View Study)
- Ulcerative colitis: A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. (View Study)
- Ulcerative colitis: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. (View Study)
- Ulcerative colitis: Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. (View Study)
- Ulcerative colitis: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study. (View Study)
- Vitiligo: Genome-wide analysis identifies a quantitative trait locus in the MHC class II region associated with generalized vitiligo age of onset. (View Study)
- Vitiligo: Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. (View Study)
- Waist-hip ratio: Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. (View Study)
(GWAS data comes from http://www.genome.gov/gwastudies/.)
Register
If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:
