arhgap10

Ensembl ID:
ENSDARG00000078326
ZFIN ID:
ZDB-GENE-060512-221
Description:
rho GTPase-activating protein 10 [Source:RefSeq peptide;Acc:NP_001038715]
Human Orthologue:
ARHGAP10
Human Description:
Rho GTPase activating protein 10 [Source:HGNC Symbol;Acc:26099]
Mouse Orthologue:
Arhgap10
Mouse Description:
Rho GTPase activating protein 10 Gene [Source:MGI Symbol;Acc:MGI:1925764]

Alleles

There are 3 alleles of this gene:

Allele name Consequence Status Availability Estimate
sa24852 Nonsense Mutation detected in F1 DNA During 2014
sa6595 Essential Splice Site Mutation detected in F1 DNA During 2014
sa14465 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa24852
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109314 Nonsense 375 764 12 23
Genomic Location:
Chromosome 1 (position 36553120)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
None
Flanking Sequence:
GGGTCTGGTTTGTGTTTTCTGATGTTTATCTCTCTCATGCAGATGCAGTG[T/A]CTCAACCGGACACATTCAAGAGAAAGAGGAAGTAAGAGACCAAATTAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa6595
Current Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
We currently estimate that this allele will be available during 2014.
Mutation:
G > A
Consequence:
Essential Splice Site
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109314 Essential Splice Site 481 764 16 23
Genomic Location:
Chromosome 1 (position 36565522)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
AGAGCCTCTAATGACATACGAGCTGTATAAGGAGTTCATCGTCCCTGCAA[G/A]TAAGGTCTTTGTCCTTGCTTTGACAATAATCAAGYAATACCCAAAACGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14465
Current Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109314 Nonsense 627 764 20 23
Genomic Location:
Chromosome 1 (position 36596242)
KASP Assay ID:
None (used for ordering genotyping assays from LGC Genomics)
KASP Sequence:
TTKCTGCTTGCTGTGACAGTGTCTCCATCCYCTGAGAGTGYAGGCCTGTG[T/A]AATGATGAGACATCAGTGGGCAGTAATGAGTCAGTCTCCTCCCAGTCMTC
Associated Phenotype:
Not determined

GWAS

This gene's human homologue has been identified in the following GWAS studies:

(GWAS data comes from http://www.genome.gov/gwastudies/.)

Register

If you would like to be informed when the status of this gene changes (for example, a new allele is generated or an allele is made available for distribution) then please enter your details below:

* quick link - http://q.sanger.ac.uk/m7cwkqyv